Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis

H Duan, Q Zhang, J Liu, R Li, D Wang, W Peng… - Pharmacological …, 2021 - Elsevier
Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

Dandelion (Taraxacum officinale L.) as a Source of Biologically Active Compounds Supporting the Therapy of Co-Existing Diseases in Metabolic Syndrome

M Kania-Dobrowolska, J Baraniak - Foods, 2022 - mdpi.com
Nowadays, many people are struggling with obesity, type 2 diabetes, and atherosclerosis,
which are called the scourge of the 21st century. These illnesses coexist in metabolic …

[HTML][HTML] Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade

QB Lu, MY Wan, PY Wang, CX Zhang, DY Xu, X Liao… - Redox biology, 2018 - Elsevier
Phenotypic switch of vascular smooth muscle cells (VSMCs) is characterized by increased
expressions of VSMC synthetic markers and decreased levels of VSMC contractile markers …

Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling

SM Abd El-Twab, OE Hussein, WG Hozayen… - Inflammation …, 2019 - Springer
Objective Chicoric acid (CA) is a natural product with promising antioxidant and anti-
inflammatory properties; however, its protective effect on methotrexate (MTX)-induced acute …

Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway

N Wang, BN Feng, B Hu, YL Cheng, YH Guo, H Qian - Food & function, 2022 - pubs.rsc.org
Chicoric acid (CA), a polyphenolic acid obtained from chicory and purple coneflower
(Echinacea purpurea), has been regarded as a nutraceutical to combat inflammation …

The bioactive effects of chicoric acid as a functional food ingredient

Y Peng, Q Sun, Y Park - Journal of Medicinal Food, 2019 - liebertpub.com
Chicoric acid, a hydroxycinnamic acid, has been reported to possess a variety of health
benefits, including antivirus, antioxidant, anti-inflammation, obesity prevention, and …

Chicoric acid alleviates lipopolysaccharide-induced acute lung injury in mice through anti-inflammatory and anti-oxidant activities

H Ding, X Ci, H Cheng, Q Yu, D Li - International Immunopharmacology, 2019 - Elsevier
Acute lung injury (ALI) is a severe clinical disease with high mortality rates. Chicoric acid
(CA), an active component extracted from traditional Chinese medicine, was suggested to …

Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways

Y Wang, Z Lin, B Zhang, Z Jiang, F Guo… - International journal of …, 2019 - mdpi.com
Background: The production and maturation of interleukin (IL)-1β, regulated by the NF-κB
and NLRP3 signaling pathways, lie at the core of gout. This study aimed to evaluate the …

A standardized extract of Echinacea purpurea containing higher chicoric acid content enhances immune function in murine macrophages and cyclophosphamide …

HV Sudeep, K Gouthamchandra… - Pharmaceutical …, 2023 - Taylor & Francis
Abstract Context Preparations of Echinacea have been used by herbalists to boost the
immune system. Objective In this study, Echinacea purpurea (L.) Moench (Asteraceae) …

Phenolic fractions from dandelion leaves and petals as modulators of the antioxidant status and lipid profile in an in vivo study

M Majewski, B Lis, J Juśkiewicz, K Ognik… - Antioxidants, 2020 - mdpi.com
Alcoholic leaf and petal fractions of Taraxacum officinale (dandelion) were previously
demonstrated to exert in vitro antioxidant and antithrombotic activities in blood plasma and …