RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Obesity affects over 2 billion people worldwide and is accompanied by peripheral
neuropathy (PN) and an associated poorer quality of life. Despite high prevalence, the …

The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral
axon injury. HuD interacts with many mRNAs, altering both stability and translation …

RNA-protein interactions permeate biology. Transcription, translation, processing, and
mRNA decay all hinge on widespread use of regulatory information decoded by RNA …

HuR is an RNA-binding protein implicated in RNA processing, stability, and translation.
Previously, we examined protein synthesis in dorsal root ganglion (DRG) neurons treated …

BACKGROUND: Chronic pain is one of the most common complaints in patients with human
immunodeficiency virus (HIV)–associated sensory neuropathy. Ryanodine receptor (RyR) …

Human immunodeficiency virus (HIV) patients treated with nucleoside reverse transcriptase
inhibitors (NRTIs), have been known to develop neuropathic pain. While there has been a …

Nucleoside reverse transcriptase inhibitors (NRTIs), drugs used to treat HIV infection, can
cause neuropathic pain (NP) and neuroinflammation. An NRTI, 2′-3′-dideoxycytidine …

Chronic pain is increasingly recognized as an important comorbidity of HIV-infected patients,
however, the exact molecular mechanisms of HIV-related pain are still elusive …

Abstract mRNA function is meticulously controlled. We provide an overview of the integral
role that posttranscriptional controls play in the perception of painful stimuli by sensory …