Relatedness is a fundamental concept in genetics but is surprisingly hard to define in a
rigorous yet useful way. Traditional relatedness coefficients specify expected genome …

Metrics derived from pedigrees are key to investigating several major issues in evolutionary
biology, including the quantitative genetic architecture of traits, inbreeding depression, and …

Local adaptation is a central feature of most species occupying spatially heterogeneous
environments, and may factor critically in responses to environmental change. However …

Archaeogenomic research has proven to be a valuable tool to trace migrations of historic
and prehistoric individuals and groups, whereas relationships within a group or burial site …

Genome‐wide association studies (GWAS) are widely used in diploid species to study
complex traits in diversity and breeding populations, but GWAS software tailored to …

Prediction of genetic merit or disease risk using genetic marker information is becoming a
common practice for selection of livestock and plant species. For the successful application …

Genetic kinship of ancient individuals can provide insights into their culture and social
hierarchy, and is relevant for downstream genetic analyses. However, estimating …

Endometriosis is a common gynecological disease associated with pelvic pain and
subfertility. We conducted a genome-wide association study (GWAS) in 3,194 individuals …

Knowledge of the genetic relatedness among individuals is essential in diverse research
areas such as behavioural ecology, conservation biology, quantitative genetics and …

The conservation of farm animal resources is important for coping with future breeding
needs and for facilitating the sustainable use of marginal areas. The increasing availability …