Relatedness in the post-genomic era: is it still useful?
D Speed, DJ Balding - Nature Reviews Genetics, 2015 - nature.com
Relatedness is a fundamental concept in genetics but is surprisingly hard to define in a
rigorous yet useful way. Traditional relatedness coefficients specify expected genome …
rigorous yet useful way. Traditional relatedness coefficients specify expected genome …
Wild pedigrees: the way forward
JM Pemberton - Proceedings of the Royal Society B …, 2008 - royalsocietypublishing.org
Metrics derived from pedigrees are key to investigating several major issues in evolutionary
biology, including the quantitative genetic architecture of traits, inbreeding depression, and …
biology, including the quantitative genetic architecture of traits, inbreeding depression, and …
Ecological genomics meets community‐level modelling of biodiversity: Mapping the genomic landscape of current and future environmental adaptation
MC Fitzpatrick, SR Keller - Ecology letters, 2015 - Wiley Online Library
Local adaptation is a central feature of most species occupying spatially heterogeneous
environments, and may factor critically in responses to environmental change. However …
environments, and may factor critically in responses to environmental change. However …
Estimating genetic kin relationships in prehistoric populations
JM Monroy Kuhn, M Jakobsson, T Günther - PloS one, 2018 - journals.plos.org
Archaeogenomic research has proven to be a valuable tool to trace migrations of historic
and prehistoric individuals and groups, whereas relationships within a group or burial site …
and prehistoric individuals and groups, whereas relationships within a group or burial site …
Software for genome‐wide association studies in autopolyploids and its application to potato
Genome‐wide association studies (GWAS) are widely used in diploid species to study
complex traits in diversity and breeding populations, but GWAS software tailored to …
complex traits in diversity and breeding populations, but GWAS software tailored to …
Bias in genomic predictions for populations under selection
Prediction of genetic merit or disease risk using genetic marker information is becoming a
common practice for selection of livestock and plant species. For the successful application …
common practice for selection of livestock and plant species. For the successful application …
KIN: a method to infer relatedness from low-coverage ancient DNA
Genetic kinship of ancient individuals can provide insights into their culture and social
hierarchy, and is relevant for downstream genetic analyses. However, estimating …
hierarchy, and is relevant for downstream genetic analyses. However, estimating …
Genome-wide association study identifies a locus at 7p15. 2 associated with endometriosis
Endometriosis is a common gynecological disease associated with pelvic pain and
subfertility. We conducted a genome-wide association study (GWAS) in 3,194 individuals …
subfertility. We conducted a genome-wide association study (GWAS) in 3,194 individuals …
Triadic IBD coefficients and applications to estimating pairwise relatedness
J Wang - Genetics Research, 2007 - cambridge.org
Knowledge of the genetic relatedness among individuals is essential in diverse research
areas such as behavioural ecology, conservation biology, quantitative genetics and …
areas such as behavioural ecology, conservation biology, quantitative genetics and …
Molecular characterization of breeds and its use in conservation
The conservation of farm animal resources is important for coping with future breeding
needs and for facilitating the sustainable use of marginal areas. The increasing availability …
needs and for facilitating the sustainable use of marginal areas. The increasing availability …