[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

P Irrgang, J Gerling, K Kocher, D Lapuente… - Science …, 2022 - science.org
RNA vaccines are efficient preventive measures to combat the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic. High levels of neutralizing SARS-CoV-2 …

Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

[HTML][HTML] Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

V Servellita, AM Syed, MK Morris, N Brazer, P Saldhi… - Cell, 2022 - cell.com
Virus-like particle (VLP) and live virus assays were used to investigate neutralizing immunity
against Delta and Omicron SARS-CoV-2 variants in 259 samples from 128 vaccinated …

Impaired detection of omicron by SARS-CoV-2 rapid antigen tests

A Osterman, I Badell, E Basara, M Stern… - Medical microbiology …, 2022 - Springer
Since autumn 2020, rapid antigen tests (RATs) have been implemented in several countries
as an important pillar of the national testing strategy to rapidly screen for infections on site …

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

ST Sonnleitner, M Prelog, S Sonnleitner… - Nature …, 2022 - nature.com
Different scenarios explaining the emergence of novel variants of concern (VOC) of the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported …

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

H Gruell, K Vanshylla, M Korenkov, P Tober-Lau… - Cell Host & Microbe, 2022 - cell.com
SARS-CoV-2 neutralizing antibodies play a critical role in COVID-19 prevention and
treatment but are challenged by viral evolution and the emergence of novel escape variants …