The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Obstacles and opportunities in a forward vision for cancer nanomedicine

I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

Environmental dimensions of the protein corona

KE Wheeler, AJ Chetwynd, KM Fahy, BS Hong… - Nature …, 2021 - nature.com
The adsorption of biomolecules to the surface of engineered nanomaterials, known as
corona formation, defines their biological identity by altering their surface properties and …

A materials-science perspective on tackling COVID-19

Z Tang, N Kong, X Zhang, Y Liu, P Hu, S Mou… - Nature Reviews …, 2020 - nature.com
The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in
providing tools and technologies for antiviral research and treatment development. In this …

In situ analysis of nanoparticle soft corona and dynamic evolution

D Baimanov, J Wang, J Zhang, K Liu, Y Cong… - Nature …, 2022 - nature.com
How soft corona, the protein corona's outer layer, contributes to biological identity of
nanomaterials is largely because capturing protein composition of the soft corona in situ …

Advances and utility of the human plasma proteome

EW Deutsch, GS Omenn, Z Sun, M Maes… - Journal of proteome …, 2021 - ACS Publications
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

Parallelized acquisition of orbitrap and astral analyzers enables high-throughput quantitative analysis

HI Stewart, D Grinfeld, A Giannakopulos… - Analytical …, 2023 - ACS Publications
The growing trend toward high-throughput proteomics demands rapid liquid
chromatography–mass spectrometry (LC–MS) cycles that limit the available time to gather …

Superparamagnetic iron oxide nanoparticles for magnetic hyperthermia: Recent advancements, molecular effects, and future directions in the omics era

C Pucci, A Degl'Innocenti, MB Gümüş… - Biomaterials Science, 2022 - pubs.rsc.org
Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted attention in the
biomedical field thanks to their ability to prompt hyperthermia in response to an alternated …

Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for their function

K Liu, R Nilsson, E Lázaro-Ibáñez, H Duàn… - Nature …, 2023 - nature.com
In terms of lipid nanoparticle (LNP) engineering, the relationship between particle
composition, delivery efficacy, and the composition of the biocoronas that form around LNPs …

Bottom-up proteomics: advancements in sample preparation

VA Duong, H Lee - International journal of molecular sciences, 2023 - mdpi.com
Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …