Background The conventional oral dosage forms are not effective in dealing with
chronopathological conditions, such as nocturnal asthma. Therefore, there is an unmet need …

Objective (s): Micelles have been studied as nanoparticulate drug delivery systems for
improving the topical ocular delivery of hydrophobic drugs. The objective of this study was to …

The objective of this study was the preparation and characterization of a sustained-release
matrix tablet containing a high-dose hydrophobic drug and its comparison with marketed …

Liqui-solid technique and solid dispersion formation are two novel approaches for
enhancement of dissolution rate of BCS class II drugs. Liqui-solid compact converts a liquid …

Valsartan is a specific angiotensin II antagonist used for the treatment of hypertension. It
suffers from low aqueous solubility and high variability in its absorption after oral …

Two 1,000 mg prolonged-release ciprofloxacin (CIP) tablets marketed in Colombia were
compared for quality control tests and dissolution profile as established in the United States …

El presente estudio se realizó con el objetivo de establecer mediante pruebas de disolución
in vitro, si dos formas farmacéuticas multifuente de liberación inmediata, de administración …

Finasteride (FNS) is a specific competitive inhibitor of steroid type-II 5α-reductase and is
widely used for the treatment of benign prostatic hyperplasia, prostate cancer, and …

Studies have shown that when compressing drugs with low aqueous solubility, the solubility
of diluents selected is very crucial as it influences the disintegration, dissolution and …

Objectives: A sustained release Gastro-bilayer floating tablets with reduced dosing
frequency and increased drug bioavailability is developed. The dosage form is suitable for …