[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Natural killer cells in COVID-19: from infection, to vaccination and therapy

A Zafarani, MH Razizadeh, S Pashangzadeh… - Future …, 2023 - Taylor & Francis
Natural killer (NK) cells are among the most important innate immunity members, which are
the first cells that fight against infected cells. The function of these cells is impaired in …

Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates

CA Schramm, D Moon, L Peyton, NS Lima… - Nature …, 2023 - nature.com
As SARS-CoV-2 variants continue evolving, testing updated vaccines in non-human
primates remains important for guiding human clinical practice. To date, such studies have …

Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes

D Gemmati, G Longo, I Gallo, JA Silva… - Frontiers in …, 2022 - frontiersin.org
Background: Development and worldwide availability of safe and effective vaccines against
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) to fight severe symptoms of …

MAIT cell compartment characteristics are associated with the immune response magnitude to the BNT162b2 mRNA anti-SARS-CoV-2 vaccine

C Boulouis, T Kammann, A Cuapio, T Parrot, Y Gao… - Molecular …, 2022 - Springer
Mucosa-associated invariant T (MAIT) cells are unconventional T cells with innate-like
capacity to rapidly respond to microbial infection via MR1-restricted antigen recognition …

Changes in peripheral immune cells after the third dose of SARS-CoV-2 mRNA-BNT162b2 vaccine and disease outcomes in cancer patients receiving immune …

F Nelli, C Signorelli, A Fabbri, D Giannarelli, A Virtuoso… - Cancers, 2023 - mdpi.com
Simple Summary International standards recommend booster immunization against SARS-
CoV-2 in advanced cancer patients undergoing active treatment. Little is known about the …

Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1

A Alrubayyi, E Touizer, D Hameiri-Bowen… - Scientific Reports, 2023 - nature.com
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of
vaccine-induced T and B cell responses and are specialized towards antibody-dependent …

Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants

S Dzanibe, AJ Wilk, S Canny, T Ranganath… - Nature …, 2024 - nature.com
While preventing vertical HIV transmission has been very successful, HIV-exposed
uninfected infants (iHEU) experience an elevated risk to infections compared to HIV …

Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations

RA Purcell, RM Theisen, KB Arnold… - Frontiers in …, 2023 - frontiersin.org
Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …

NK cells in COVID-19—from disease to vaccination

Q Hammer, A Cuapio, J Bister… - Journal of Leukocyte …, 2023 - academic.oup.com
Natural killer cells participate in the host innate immune response to viral infection.
Conversely, natural killer cell dysfunction and hyperactivation can contribute to tissue …