APOA1: a protein with multiple therapeutic functions
Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …
Pathophysiology of thrombotic thrombocytopenic purpura
JE Sadler - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif,
member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic …
member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic …
Endothelial activation and blood–brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells
Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen
receptor–modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in …
receptor–modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in …
Inflammation, von Willebrand factor, and ADAMTS13
J Chen, DW Chung - Blood, The Journal of the American …, 2018 - ashpublications.org
Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand
factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF …
factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF …
The different facets of dyslipidemia and hypertension in atherosclerosis
J Hurtubise, K McLellan, K Durr, O Onasanya… - Current atherosclerosis …, 2016 - Springer
Atherosclerosis is the narrowing of arteries due to the accumulation of macrophages
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …
The role of von Willebrand factor in vascular inflammation: from pathogenesis to targeted therapy
F Gragnano, S Sperlongano, E Golia… - Mediators of …, 2017 - Wiley Online Library
Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of
vascular inflammation. Recent studies highlight the involvement of VWF and its regulator …
vascular inflammation. Recent studies highlight the involvement of VWF and its regulator …
Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis
Purpose We sought to determine whether an early high-density lipoprotein cholesterol (HDL-
C) measurement at emergency department (ED) admission is prognostic of multiorgan …
C) measurement at emergency department (ED) admission is prognostic of multiorgan …
Platelets and von Willebrand factor in atherogenesis
MD Wu, TM Atkinson, JR Lindner - Blood, The Journal of the …, 2017 - ashpublications.org
The role of platelet adhesion, activation, and aggregation in acute atherothrombotic events
such as myocardial infarction and stroke is well established. There is increasing evidence …
such as myocardial infarction and stroke is well established. There is increasing evidence …
Role of von Willebrand factor in COVID-19 associated coagulopathy
ZW Mei, XMR van Wijk, HP Pham… - The journal of applied …, 2021 - academic.oup.com
Background COVID-19, the disease caused by SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) can present with symptoms ranging from none to severe …
syndrome coronavirus 2) can present with symptoms ranging from none to severe …
Biological consequences of dysfunctional HDL
A Pirillo, AL Catapano… - Current medicinal …, 2019 - ingentaconnect.com
Epidemiological studies have suggested an inverse correlation between high-density
lipoprotein (HDL) cholesterol levels and the risk of cardiovascular disease. HDLs promote …
lipoprotein (HDL) cholesterol levels and the risk of cardiovascular disease. HDLs promote …