The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

Type 2 diabetes

S Chatterjee, K Khunti, MJ Davies - The lancet, 2017 - thelancet.com
Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …

Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes …

DR Matthews, PM Paldánius, P Proot, YT Chiang… - The Lancet, 2019 - thelancet.com
Background Early treatment intensification leading to sustained good glycaemic control is
essential to delay diabetic complications. Although initial combination therapy has been …

Glycemic control and risk of infections among people with type 1 or type 2 diabetes in a large primary care cohort study

JA Critchley, IM Carey, T Harris, S DeWilde… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Diabetes mellitus (DM) increases the risk of infections, but the effect of better
control has not been thoroughly investigated. RESEARCH DESIGN AND METHODS With …

Differentiation of diabetes by pathophysiology, natural history, and prognosis

JS Skyler, GL Bakris, E Bonifacio, T Darsow… - Diabetes, 2017 - Am Diabetes Assoc
The American Diabetes Association, JDRF, the European Association for the Study of
Diabetes, and the American Association of Clinical Endocrinologists convened a research …

Therapeutic inertia in the treatment of hyperglycaemia in patients with type 2 diabetes: a systematic review

K Khunti, MB Gomes, S Pocock… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aims Therapeutic inertia, defined as the failure to initiate or intensify therapy in a timely
manner according to evidence‐based clinical guidelines, is a key reason for uncontrolled …

Trends in incidence, prevalence and prescribing in type 2 diabetes mellitus between 2000 and 2013 in primary care: a retrospective cohort study

M Sharma, I Nazareth, I Petersen - BMJ open, 2016 - bmjopen.bmj.com
Objective To investigate trends in incident and prevalent diagnoses of type 2 diabetes
mellitus (T2DM) and its pharmacological treatment between 2000 and 2013. Design …

Evaluation of the cascade of diabetes care in the United States, 2005-2016

P Kazemian, FM Shebl, N McCann… - JAMA internal …, 2019 - jamanetwork.com
Importance Treatment advances in diabetes can meaningfully improve outcomes only if they
effectively reach the populations at risk. Objectives To evaluate whether the cascade of US …

Identification of barriers to insulin therapy and approaches to overcoming them

D Russell‐Jones, F Pouwer… - Diabetes, Obesity and …, 2018 - Wiley Online Library
Poor glycaemic control in type 2 diabetes (T2D) is a global problem despite the availability
of numerous glucose‐lowering therapies and clear guidelines for T2D management …

[HTML][HTML] Pharmacologic management of type 2 diabetes mellitus: available therapies

J Thrasher - The American journal of cardiology, 2017 - Elsevier
Choices for the treatment of type 2 diabetes mellitus (T2DM) have multiplied as our
understanding of the underlying pathophysiologic defects has evolved. Treatment should …