Melatonin as a potential approach to anxiety treatment

K Repova, T Baka, K Krajcirovicova, P Stanko… - International journal of …, 2022 - mdpi.com
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review

F Simko, T Baka, L Paulis… - Journal of pineal …, 2016 - Wiley Online Library
Elevated heart rate is a risk factor for cardiovascular and all‐cause mortalities in the general
population and various cardiovascular pathologies. Insufficient heart rate decline during the …

[PDF][PDF] Blood pressure regulation in stress: focus on nitric oxide-dependent mechanisms

A Puzserova, I Bernatova - Physiol Res, 2016 - paulwulleman.be
Blood Pressure Regulation in Stress: Focus on Nitric Oxide-Dependent Mechanisms Page 1
PHYSIOLOGICAL RESEARCH ISSN 0862-8408(print) ISSN 1802-9973(online) © 2016 Institute …

Melatonin and metabolic regulation: a review

M Navarro-Alarcón, FJ Ruiz-Ojeda… - Food & function, 2014 - pubs.rsc.org
Human life expectancy has increased over the past 50 years due to scientific and medical
advances and higher food availability. However, overweight and obesity affect more than …

Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol‐induced heart failure

F Simko, KR Bednarova… - Journal of Pineal …, 2014 - Wiley Online Library
Melatonin was previously shown to reduce blood pressure and left ventricular (LV)
remodeling in several models of experimental heart damage. This study investigated …

Cardiovascular therapeutics: A new potential for anxiety treatment?

K Repova, S Aziriova, K Krajcirovicova… - Medicinal Research …, 2022 - Wiley Online Library
Besides the well‐recognized risk factors, novel conditions increasing cardiovascular
morbidity and mortality are emerging. Undesirable emotions and behavior such as anxiety …

[HTML][HTML] Effect of sacubitril/valsartan on the hypertensive heart in continuous light-induced and lactacystin-induced pre-hypertension: Interactions with the renin …

F Simko, P Stanko, K Repova, T Baka… - Biomedicine & …, 2024 - Elsevier
This study investigated whether sacubitril/valsartan or valsartan are able to prevent left
ventricular (LV) fibrotic remodelling and dysfunction in two experimental models of pre …

Hypertension and cardiovascular remodelling in rats exposed to continuous light: protection by ACE‐inhibition and melatonin

F Simko, O Pechanova… - Mediators of …, 2014 - Wiley Online Library
Exposure of rats to continuous light attenuates melatonin production and results in
hypertension development. This study investigated whether hypertension induced by …

Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light

YL Tain, YJ Lin, JYH Chan, CT Lee… - Biology of …, 2017 - academic.oup.com
Hypertension can originate from early-life insults, whereas maternal melatonin therapy can
be protective in a variety of models of programmed hypertension. We hypothesize that …

Hypotensive effects of melatonin in rats: Focus on the model, measurement, application, and main mechanisms

D Cvikova, H Sutovska, K Babarikova… - Hypertension Research, 2022 - nature.com
The hypotensive effects of melatonin are based on a negative correlation between
melatonin levels and blood pressure in humans. However, there is a positive correlation in …