Obesity markedly increases the odds of developing depression. Depressed mood not only
impairs motivation, quality of life and overall functioning but also increases the risks of …

About 280 million people suffer from depression as the most common neurological disorder
and the most common cause of death worldwide. Exercise with serotonin released in the …

Background: Epigenetic drugs like sodium butyrate (NaB) show antidepressant-like effects
in preclinical studies, but the exact molecular mechanisms of the antidepressant effects …

Depression is a common mental disorder in which patients often experience feelings of
sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for …

Neuropeptide Y (NPY), a neuropeptide highly conserved throughout evolution, is present at
high levels in the central nervous system (CNS), as well as in peripheral tissues such as the …

There is extensive evidence that NPY in the brain can modulate the responses to stress and
play a critical role in resistance to, or recovery from, harmful effects of stress. Development of …

Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate
various biological effects including membrane excitability, synaptic transmission and …

Background: Telomeres are protective DNA-protein complexes at the ends of each
chromosome, maintained primarily by the enzyme telomerase. Shortening of the blood …

Abstract Bipolar disorder (BPD), schizophrenia (SCZ) and unipolar major depressive
disorder (MDD) are primary psychiatric disorders sharing substantial genetic risk factors. We …

A peptide composed of a 36 amino acid called Neuropeptide Y (NPY) is employed in a
variety of physiological processes to manage and treat conditions affecting the endocrine …