Adaptive responses to low doses of radiation or chemicals: their cellular and molecular mechanisms

Y Guéguen, A Bontemps, TG Ebrahimian - Cellular and Molecular Life …, 2019 - Springer
This article reviews the current knowledge on the mechanisms of adaptive response to low
doses of ionizing radiation or chemical exposure. A better knowledge of these mechanisms …

Daphnoretin arrests the cell cycle and induces apoptosis in human breast cancer cells

Q Xie, X Fan, Y Han, BX Wu, B Zhu - Journal of Natural Products, 2022 - ACS Publications
Emerging evidence has shown that daphnoretin, one of the main active ingredients of
Daphne giraldii Nitsche, processes antitumor activities in several tumor cells (eg, colon …

[HTML][HTML] Bax/Bcl-2 expression ratio in prediction of response to breast cancer radiotherapy

H Azimian, M Dayyani, MTB Toossi… - Iranian journal of basic …, 2018 - ncbi.nlm.nih.gov
Objective (s): Radiotherapy is one of the most effective modalities of cancer therapy, but
clinical responses of individual patients varies considerably. To enhance treatment …

Global gene expression alterations as a crucial constituent of human cell response to low doses of ionizing radiation exposure

M Sokolov, R Neumann - International Journal of Molecular Sciences, 2015 - mdpi.com
Exposure to ionizing radiation (IR) is inevitable to humans in real-life scenarios; the hazards
of IR primarily stem from its mutagenic, carcinogenic, and cell killing ability. For many …

[HTML][HTML] Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?

E Decrock, D Hoorelbeke, R Ramadan… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Although radiotherapy is commonly used to treat cancer, its beneficial outcome is frequently
hampered by the radiation resistance of tumor cells and adverse reactions in normal tissues …

Venetoclax cooperates with ionizing radiation to attenuate diffuse midline glioma tumor growth

K Madhavan, I Balakrishnan, S Lakshmanachetty… - Clinical Cancer …, 2022 - AACR
Purpose: Tumor relapse after radiotherapy is a major hurdle in treating pediatric H3K27M-
mutant diffuse midline gliomas (DMG). Radiotherapy-induced stress increases association …

Gold (III) complexes with phenanthroline-derivatives ligands induce apoptosis in human colorectal and breast cancer cell lines

MG Milutinović, NN Milivojević, NM Đorđević… - Journal of …, 2022 - Elsevier
Due to their promising effects, gold (III) complexes recently drew increasing attention in the
design of new metal-based anticancer therapeutics. Two gold (III) complexes, square-planar …

The Cytokine Profile of Chronically Irradiated People in the Long Term after the Beginning of Irradiation

EA Kodintseva, AA Akleyev, EA Blinova - Biology Bulletin, 2022 - Springer
The cytokine network is an important integrative and regulatory mechanism of the immune,
endocrine, and nervous systems. Disturbances of this mechanism could play a role in the …

Role of AKT and ERK pathways in controlling sensitivity to ionizing radiation and adaptive response induced by low-dose radiation in human immune cells

HS Park, GE You, KH Yang, JY Kim, S An… - European Journal of …, 2015 - Elsevier
Despite many studies of the effect of ionizing radiation, biological mechanisms of action
might differ greatly depend on dose, dose rate, and cell type. This study was performed to …

[HTML][HTML] Chromosomal instability in various generations of human mesenchymal stem cells following the therapeutic radiation

MS Moghadam, H Azimian, JT Afshari… - Stem Cells …, 2023 - ncbi.nlm.nih.gov
Background Radiotherapy is a crucial treatment for most malignancies. However, it can
cause several side effects, including the development of secondary malignancies due to …