Teleosts lack a hypophyseal portal system and hence neurohormones are carried by nerve
fibers from the preoptic region to the pituitary. The various cell types in the teleost pituitary …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

The orphan nuclear receptor steroidogenic factor 1 (SF-1, also called Ad4BP, encoded by
the NR5A1 gene) is an essential regulator of endocrine development and function. Initially …

To provide a multi-omics resource and investigate transcriptional regulatory mechanisms,
we profile the transcriptome, chromatin accessibility, and methylation status of over 70,000 …

The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …

The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive
physiology. Though the two hormones are produced by the same cell type, often in response …

Regulation of follicle-stimulating hormone (FSH) synthesis is a central point of convergence
for signals controlling reproduction. The FSHβ subunit is primarily regulated by …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

FSH is produced by the pituitary gonadotrope to regulate gametogenesis. Steroid hormones,
including androgens, progestins, and glucocorticoids, have all been shown to stimulate …

FSH is a critical hormone regulator of gonadal function that is secreted from the pituitary
gonadotrope cell. Human patients and animal models with mutations in the LHX3 LIM …