Over the years, several tumor biomarkers have been suggested to foresee the prognosis
oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to …

The Th2 cytokines, interleukin (IL)-4 and-13, are structurally and functionally related. They
regulate immune responses and the immune microenvironment, not only under normal …

Oral squamous cell carcinoma (OSCC) represents the sixth most common cancer,
accounting for 2–4% of all malignancies worldwide. The overall survival rate of less than …

Background Oral squamous cell carcinoma (OSCC) accounts over 90% of malignant
neoplasms of the oral cavity. This pathological entity is associated to a high mortality rate …

Background While observational studies and experimental data suggest a link between oral
lichen planus (OLP) and oral cavity cancer (OCC), the causal relationship and the role of …

Simple Summary Group 2 innate lymphoid cells (ILC2s), like other ILCs, are a new resident
cell subset of innate immunity that provides the first line of defense against pathogens such …

A growing body of evidence suggests that pathological lesions express tissue-specific
molecular targets or biomarkers within the tissue. Interleukin-4 receptor (IL-4R) is …

Abstract IL-4 receptor (IL-4R) is commonly up-regulated on tumor cells, and interactions
between the receptor and Interleukin-4 (IL-4) can induce the expression of anti-apoptotic …

Abstract Background The interleukin (IL)-4/IL-13/signal transducer and activator of
transcription (STAT) 6 signaling pathway and the SOCS3 gene, one of its main regulators …

Abstract IL-13 receptor subunit alpha-2 (IL13Rα2) is associated with poor prognosis in some
cancers. However, the role of IL13Rα2 in lung cancer remains unknown. We showed that …