A review on novel methodologies for drug nanoparticle preparation: Microfluidic approach
The intrinsic limitations of conventional dosages have facilitated the emergence of novel
drug delivery methodologies. Drug nanonization and encapsulation in polymeric …
drug delivery methodologies. Drug nanonization and encapsulation in polymeric …
Statistically designed dexibuprofen loaded solid lipid nanoparticles for enhanced oral bioavailability
Abstract Dexibuprofen (DBPN), a non-steroidal anti-inflammatory drug (NSAID), exhibit its
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
Double flow focusing microfluidic-assisted based preparation of methotrexate–loaded liposomal nanoparticles: Encapsulation efficacy, drug release and stability
This study presents a novel and facile route to produce the methotrexate (MTX) loaded
liposomal particles using the double flow focusing microfluidic (double-MHFF) device in a …
liposomal particles using the double flow focusing microfluidic (double-MHFF) device in a …
Oxyberberine an oxoderivative of berberine confers neuroprotective effects in controlled-cortical impact mouse model of traumatic brain injury
Background Traumatic brain injury (TBI) is known as a silent epidemic that causes many
deaths and disabilities worldwide. We examined the response of oxyberberine (OBB) in …
deaths and disabilities worldwide. We examined the response of oxyberberine (OBB) in …
Solubility and Dissolution Enhancement of Dexibuprofen with Hydroxypropylbetacyclodextrin (HPβCD) and Poloxamers (188/407) Inclusion Complexes: Preparation …
The objective of this study was to improve the dissolution and solubility of dexibuprofen
(DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to …
(DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to …
Nanonized carbamazepine for nose-to-brain delivery: Pharmaceutical formulation development
A Bonaccorso, MR Gigliobianco… - Pharmaceutical …, 2023 - Taylor & Francis
Epilepsy is one of the most common neurological disorders in the world. The therapeutic
treatment is challenging since conventional drugs have limited efficacy and several side …
treatment is challenging since conventional drugs have limited efficacy and several side …
Microfluidics nanoprecipitation of telmisartan nanoparticles: Effect of process and formulation parameters
A continuous microfluidic nanoprecipitation process has been investigated to prepare
nanosized particles of a poorly water-soluble drug telmisartan (TEL), thereby enhancing its …
nanosized particles of a poorly water-soluble drug telmisartan (TEL), thereby enhancing its …
Biodegradable Polymers-Based Smart Nanocrystals for Loxoprofen Delivery with Enhanced Solubility: Design, Fabrication and Physical Characterizations
BA Khan, H Khalid, MK Khan, KM Hosny, S Khan… - Polymers, 2022 - mdpi.com
Nanocrystals are carrier-free, submicron-sized, colloidal drug delivery systems with particle
sizes in the mean nanometer range. Nanocrystals have high bioavailability and fast …
sizes in the mean nanometer range. Nanocrystals have high bioavailability and fast …
[PDF][PDF] 纳米晶体稳定性影响因素及稳定化措施研究进展
陈焕， 叶凡， 柯俊雄， 党云洁， 杜青 - 中国药学杂志, 2023 - journal11.magtechjournal.com
摘要纳米晶体是指粒径小于1μm 的药物晶体颗粒, 较小的尺寸以及独特的物理化学性质有效地
改善了药物溶解度低和生物利用度低的问题, 使纳米晶体技术在新型制剂研发方面极具潜力 …
改善了药物溶解度低和生物利用度低的问题, 使纳米晶体技术在新型制剂研发方面极具潜力 …
[PDF][PDF] Enhanced dissolution rate of Ketoprofen by fabricating into smart nanocrystals.
J Khan, S Bashir, MA Khan, R Ghaffar… - Pakistan Journal of …, 2019 - researchgate.net
The low bioavailability of Ketoprofen is associated with its hydrophobic nature that can be
solved by nanonization. For this purpose, a polymeric solution with drug concentration of …
solved by nanonization. For this purpose, a polymeric solution with drug concentration of …