Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

Cerebral small vessel diseases (SVDs) range broadly in etiology but share remarkably
overlapping pathology. Features of SVD including enlarged perivascular spaces (EPVS) …

Current theories of the glymphatic system (GS) hypothesize that it relies on cerebrospinal
fluid (CSF) circulation to disseminate growth factors and remove metabolic waste from the …

Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …

In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Sleep, a vital process of human being, is carefully orchestrated by the brain and consists of
cyclic transitions between rapid eye movement (REM) and non-REM (NREM) sleep …

When considered separately from cardiovascular disease, stroke is the third leading cause
of death in the US and is the leading cause of long-term disability in adults. New approaches …

The normal sleep-wake cycle is characterized by diurnal variations in blood pressure, heart
rate, and cardiac events. Sleep apnea disrupts the normal sleep-heart interaction, and the …

The analysis of cerebral perivascular spaces (PVS) using magnetic resonance imaging
(MRI) allows to explore in vivo their contributions to neurological disorders. To date the …

Background and Objectives Alzheimer disease (AD) and other forms of dementia represent
a rising global public health crisis. Because effective treatments to prevent, cure, or slow …