Transposable elements in Drosophila

V Mérel, M Boulesteix, M Fablet, C Vieira - Mobile DNA, 2020 - Springer
Drosophila has been studied as a biological model for many years and many discoveries in
biology rely on this species. Research on transposable elements (TEs) is not an exception …

Programmed translational frameshifting

PJ Farabaugh - Microbiological reviews, 1996 - Am Soc Microbiol
The ribosome is a molecular machine which evolved to translate RNA messages faithfully
and efficiently into a protein product. However, the demands of speed and accuracy conffict …

Tau activates transposable elements in Alzheimer's disease

C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett… - Cell reports, 2018 - cell.com
Aging and neurodegenerative disease are characterized by genomic instability in neurons,
including aberrant activation and mobilization of transposable elements (TEs). Integrating …

Refinement of tools for targeted gene expression in Drosophila

BD Pfeiffer, TTB Ngo, KL Hibbard, C Murphy, A Jenett… - Genetics, 2010 - academic.oup.com
A wide variety of biological experiments rely on the ability to express an exogenous gene in
a transgenic animal at a defined level and in a spatially and temporally controlled pattern …

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition

DD Luan, MH Korman, JL Jakubczak, TH Eickbush - Cell, 1993 - cell.com
R2 is a non-LTR retrotransposable element that inserts at a specific site in the 28s rRNA
genes of most insects. We have expressed the open reading frame of the R2 element from …

Identification of four conserved motifs among the RNA‐dependent polymerase encoding elements.

O Poch, I Sauvaget, M Delarue, N Tordo - The EMBO journal, 1989 - embopress.org
Four consensus sequences are conserved with the same linear arrangement in RNA‐
dependent DNA polymerases encoded by retroid elements and in RNA‐dependent RNA …

Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot

I Brierley, P Digard, SC Inglis - Cell, 1989 - Elsevier
The genomic RNA of the coronavirus IBV contains an efficient ribosomal frameshifting signal
at the junction of two overlapping open reading frames. We have defined by deletion …

SQuIRE reveals locus-specific regulation of interspersed repeat expression

WR Yang, D Ardeljan, CN Pacyna… - Nucleic acids …, 2019 - academic.oup.com
Transposable elements (TEs) are interspersed repeat sequences that make up much of the
human genome. Their expression has been implicated in development and disease …

Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region

T Jacks, HD Madhani, FR Masiarz, HE Varmus - Cell, 1988 - Elsevier
The gag-pol protein of Rous sarcoma virus (RSV), the precursor to the enzymes responsible
for reverse transcription and integration, is expressed from two genes that lie in different …

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

PK Geyer, VG Corces - Genes & development, 1992 - genesdev.cshlp.org
Expression of the yellow (y) gene of Drosophila melanogaster is controlled by a series of
tissue-specific transcriptional enhancers located in the 5'region and intron of the gene …