The Akt pathway in oncology therapy and beyond
GM Nitulescu, M Van De Venter… - International …, 2018 - spandidos-publications.com
Protein kinase B (Akt), similar to many other protein kinases, is at the crossroads of cell
death and survival, playing a pivotal role in multiple interconnected cell signaling …
death and survival, playing a pivotal role in multiple interconnected cell signaling …
Ecotoxicity of plant extracts and essential oils: A review
CA Ferraz, MR Pastorinho, A Palmeira-de-Oliveira… - Environmental …, 2022 - Elsevier
Plant-based products such as essential oils and other extracts have been used for centuries
due to their beneficial properties. Currently, their use is widely disseminated through a …
due to their beneficial properties. Currently, their use is widely disseminated through a …
Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models
Pyrrolizidine alkaloids (PAs) are a widespread class of hepatotoxic heterocyclic organic
compounds found in approximately 3% of world flora. Some PAs have been shown to have …
compounds found in approximately 3% of world flora. Some PAs have been shown to have …
Synthesis, characterization, antimicrobial and antiproliferative activity evaluation of Cu (II), Co (II), Zn (II), Ni (II) and Pt (II) complexes with isoniazid-derived compound
E Pahonțu, DC Ilieș, S Shova, C Oprean, V Păunescu… - Molecules, 2017 - mdpi.com
Hydrazone complexes of Cu (II), Co (II), Zn (II), Ni (II) and Pt (II) with N-isonicotinoyl-N′-(3-
metoxy-2 hydroxybenzaldehyde)-hydrazone (HL) were synthesized and characterized by …
metoxy-2 hydroxybenzaldehyde)-hydrazone (HL) were synthesized and characterized by …
Assembly and Annotation of a Draft Genome of the Medicinal Plant Polygonum cuspidatum
Y Zhang, L Zheng, Y Zheng, C Zhou, P Huang… - Frontiers in plant …, 2019 - frontiersin.org
Polygonum cuspidatum (Japanese knotweed, also known as Huzhang in Chinese), a plant
that produces bioactive components such as stilbenes and quinones, has long been …
that produces bioactive components such as stilbenes and quinones, has long been …
[PDF][PDF] Cytotoxic and apoptogenic properties of Dracocephalum kotschyi aerial part different fractions on calu-6 and mehr-80 lung cancer cell lines.
TA Sani, E Mohammadpour, A Mohammadi… - Farmacia, 2017 - researchgate.net
Dracocephalum kotschyi is one of the Iranian medicinal plants. The aim of this study was to
assess in vitro, the cytotoxic, antiproliferative and apoptotic effects of this plant against lung …
assess in vitro, the cytotoxic, antiproliferative and apoptotic effects of this plant against lung …
Molecular docking and screening studies of new natural sortase A inhibitors
G Nitulescu, IM Nicorescu, OT Olaru… - International Journal of …, 2017 - mdpi.com
To date, multi-drug resistant bacteria represent an increasing health threat, with a high
impact on mortality, morbidity, and health costs on a global scale. The ability of bacteria to …
impact on mortality, morbidity, and health costs on a global scale. The ability of bacteria to …
A novel antitumor protein from the mushroom Pholiota nameko induces apoptosis of human breast adenocarcinoma MCF-7 cells in vivo and modulates cytokine …
Y Zhang, YN Zhang, W Gao, R Zhou, F Liu… - International Journal of …, 2020 - Elsevier
Breast cancer is the most common malignant tumor in women and one of the three most
common cancers worldwide. It is a life-threatening disease among women and the leading …
common cancers worldwide. It is a life-threatening disease among women and the leading …
Targeting the hallmarks of cancer: The effects of silibinin on proliferation, cell death, angiogenesis, and migration in colorectal cancer
S Sameri, C Mohammadi, M Mehrabani… - … Medicine and Therapies, 2021 - Springer
Background Silibinin, as a chemopreventive agent, has shown anti-cancer efficacy against
different types of cancers. In the present study, we investigated the anti-cancer activities of …
different types of cancers. In the present study, we investigated the anti-cancer activities of …
Comparing the sensitivity of aquatic organisms relative to Daphnia sp. toward essential oils and crude extracts: A meta-analysis
S Afonso, V Ferreira, M Moreira-Santos - Science of The Total Environment, 2024 - Elsevier
Interest on aromatic and medicinal plants (AMP)-based products, especially crude extracts
(CE) and essential oils (EO), has increased over recent years due to their bioactive and …
(CE) and essential oils (EO), has increased over recent years due to their bioactive and …