Peroxiredoxins as potential targets for cardiovascular disease

SJ Jeong, JG Park, GT Oh - Antioxidants, 2021 - mdpi.com
Increased oxidative stress (OS) is considered a common etiology in the pathogenesis of
cardiovascular disease (CVD). Therefore, the precise regulation of reactive oxygen species …

Therapeutic efficacy of antioxidants in ameliorating obesity phenotype and associated comorbidities

S Tun, CJ Spainhower, CL Cottrill… - Frontiers in …, 2020 - frontiersin.org
Obesity has been a worldwide epidemic for decades. Despite the abundant increase in
knowledge regarding the etiology and pathogenesis of obesity, the prevalence continues to …

[HTML][HTML] Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase …

MH Kim, JB Seong, JW Huh, YC Bae, HS Lee, DS Lee - Redox biology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver
disease globally. NAFLD—which can develop into liver fibrosis, nonalcoholic …

Anti-Obesity Effect of Dictyophora indusiata Mushroom Polysaccharide (DIP) in High Fat Diet-Induced Obesity via Regulating Inflammatory Cascades and Intestinal …

S Kanwal, S Aliya, Y Xin - Frontiers in Endocrinology, 2020 - frontiersin.org
Obesity is a multifactorial metabolic disorder characterized by low-grade chronic
inflammation, hyper-permeability of the gut epithelium, and perturbation of the intestinal …

Knockout mouse models for peroxiredoxins

YJ Lee - Antioxidants, 2020 - mdpi.com
Peroxiredoxins (PRDXs) are members of a highly conserved peroxidase family and maintain
intracellular reactive oxygen species (ROS) homeostasis. The family members are …

Macrophage peroxiredoxin 5 deficiency promotes lung cancer progression via ROS-dependent M2-like polarization

JB Seong, B Kim, S Kim, MH Kim, YH Park… - Free Radical Biology …, 2021 - Elsevier
Strategies for cancer treatment have traditionally focused on suppressing cancer cell
behavior, but many recent studies have demonstrated that regulating the tumor …

[HTML][HTML] The mammalian peroxisomal membrane is permeable to both GSH and GSSG–Implications for intraperoxisomal redox homeostasis

MJ Ferreira, TA Rodrigues, AG Pedrosa, L Gales… - Redox Biology, 2023 - Elsevier
Despite the large amounts of H 2 O 2 generated in mammalian peroxisomes, cysteine
residues of intraperoxisomal proteins are maintained in a reduced state. The biochemistry …

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota

AU Rehman, AI Khan, Y Xin, W Liang - AMB Express, 2022 - Springer
Edible mushrooms have now been suggested as promising sources of biological functional
ingredients and are the subject of the most recent nutrition research and novel functional …

Plasma peroxiredoxin changes and inflammatory cytokines support the involvement of neuro-inflammation and oxidative stress in Autism Spectrum Disorder

PM Abruzzo, A Matte, A Bolotta, E Federti… - Journal of translational …, 2019 - Springer
Background It has been established that children with Autism Spectrum Disorders (ASD) are
affected by oxidative stress, the origin of which is still under investigation. In the present …

Soybean soluble polysaccharides enhance bioavailability of genistein and its prevention against obesity and metabolic syndrome of mice with chronic high fat …

Y Lu, A Zhao, Y Wu, Y Zhao, X Yang - Food & function, 2019 - pubs.rsc.org
This study aimed to explore a novel strategy for the simultaneous consumption of soluble
soybean polysaccharides (SSPS) and insoluble genistein to improve the bioavailability of …