Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Long noncoding RNA (lncRNA)-mediated competing endogenous RNA networks provide novel potential biomarkers and therapeutic targets for colorectal cancer
Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …
MicroRNAs in cancer: biomarkers, functions and therapy
The emergence of microRNAs has been one of the defining developments in cancer biology
over the past decade, and the explosion of knowledge in this area has brought forward new …
over the past decade, and the explosion of knowledge in this area has brought forward new …
[HTML][HTML] The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
Recently, the long non-coding RNA (lncRNA) H19 has been identified as an oncogenic
gene in multiple cancer types and elevated expression of H19 was tightly linked to …
gene in multiple cancer types and elevated expression of H19 was tightly linked to …
Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
EMT as the ultimate survival mechanism of cancer cells
Epithelial cancers make up the vast majority of cancer types and, during the transition from
benign adenoma to malignant carcinoma and metastasis, epithelial tumor cells acquire a de …
benign adenoma to malignant carcinoma and metastasis, epithelial tumor cells acquire a de …
The regulatory role of microRNAs in EMT and cancer
A Zaravinos - Journal of oncology, 2015 - Wiley Online Library
The epithelial to mesenchymal transition (EMT) is a powerful process in tumor invasion,
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …
Regulation of epithelial–mesenchymal and mesenchymal–epithelial transitions by microRNAs
S Lamouille, D Subramanyam, R Blelloch… - Current opinion in cell …, 2013 - Elsevier
Epithelial–mesenchymal transition (EMT) and the reverse process, mesenchymal–epithelial
transition (MET), are essential during development and in the regulation of stem cell …
transition (MET), are essential during development and in the regulation of stem cell …
A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells
JM David, C Dominguez, KK McCampbell… - …, 2017 - Taylor & Francis
Mesenchymalization is a cellular and molecular program in which epithelial cells
progressively lose their well-differentiated phenotype and adopt mesenchymal …
progressively lose their well-differentiated phenotype and adopt mesenchymal …