Impact of NQO1 dysregulation in CNS disorders
L Yuhan, M Khaleghi Ghadiri, A Gorji - Journal of Translational Medicine, 2024 - Springer
Abstract NAD (P) H Quinone Dehydrogenase 1 (NQO1) plays a pivotal role in the regulation
of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress …
of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress …
[HTML][HTML] An atlas of the heterogeneous viscoelastic brain with local power-law attenuation synthesised using Prony-series
O Morrison, M Destrade, BB Tripathi - Acta Biomaterialia, 2023 - Elsevier
This review addresses the acute need to acknowledge the mechanical heterogeneity of
brain matter and to accurately calibrate its local viscoelastic material properties accordingly …
brain matter and to accurately calibrate its local viscoelastic material properties accordingly …
Energy-absorbing limitations of hard hat safety helmets in mitigating trauma from falling objects
The aim of the study was to analyze the effectiveness of hard hat helmets in mitigating head
injuries from high-energy falling objects through a real-world case study, advanced …
injuries from high-energy falling objects through a real-world case study, advanced …
Experimental and computational approach to human brain modelling–aHEAD
The human head is a highly complex structure, with a combination of hard and soft tissues
and a variety of materials and interactions. Many researchers have used computational …
and a variety of materials and interactions. Many researchers have used computational …
[HTML][HTML] Development, validation and a case study: The female finite element head model (FeFEHM)
Background and objective: Traumatic brain injuries are one of the leading causes of death
and disability in the world. To better understand the interactions and forces applied in …
and disability in the world. To better understand the interactions and forces applied in …
Revealing the role of material properties in impact-related injuries: Investigating the influence of brain and skull density variations on head injury severity
Traumatic brain injuries (TBI) resulting from head impacts are a major public health concern,
which prompted our research to investigate the complex relationship between the material …
which prompted our research to investigate the complex relationship between the material …
[HTML][HTML] Characterization and selection of a skull surrogate for the development of a biofidelic head model
T Tenio, S Boakye-Yiadom - Journal of the Mechanical Behavior of …, 2024 - Elsevier
This research paper explores the advancement of physical models simulating the human
skull-brain complex, focusing on applications in simulating mild Traumatic Brain Injury …
skull-brain complex, focusing on applications in simulating mild Traumatic Brain Injury …
Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression injury
RD González-Cruz, Y Wan, A Burgess, D Calvao… - Plos one, 2024 - journals.plos.org
Sustained compressive injury (SCI) in the brain is observed in numerous injury and
pathological scenarios, including tumors, ischemic stroke, and traumatic brain injury-related …
pathological scenarios, including tumors, ischemic stroke, and traumatic brain injury-related …
[HTML][HTML] Excision of whole intact mouse brain
DB MacManus - MethodsX, 2023 - Elsevier
Mechanical characterization experiments of brain tissue are performed to understand the
mechanical behavior of brain tissue during normal physiology and pathophysiological …
mechanical behavior of brain tissue during normal physiology and pathophysiological …
Accuracy and efficiency of finite element head models: The role of finite element formulation and material laws
Traumatic brain injury is a significant problem worldwide. In the United States of America,
around 1.7 million cases are documented annually, displaying the need for a deeper …
around 1.7 million cases are documented annually, displaying the need for a deeper …