[HTML][HTML] Human milk microbiome: from actual knowledge to future perspective

M Selma-Royo, JC Lerma, E Cortes-Macias… - Seminars in …, 2021 - Elsevier
Human milk is the gold standard for infant nutrition during the first months of life since it is
perfectly adapted to the neonatal nutritional requirements and supports infant growth and …

Understanding viral and immune interplay during vertical transmission of HIV: implications for cure

O Amin, J Powers, KM Bricker, A Chahroudi - Frontiers in Immunology, 2021 - frontiersin.org
Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …

HIV-specific antibodies capable of ADCC are common in breastmilk and are associated with reduced risk of transmission in women with high viral loads

J Mabuka, R Nduati, K Odem-Davis, D Peterson… - PLoS …, 2012 - journals.plos.org
There are limited data describing the functional characteristics of HIV-1 specific antibodies in
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …

The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV

LF Johnson, K Stinson, ML Newell… - JAIDS Journal of …, 2012 - journals.lww.com
Background: The prevention of mother-to-child transmission (PMTCT) of HIV has been
focused mainly on women who are HIV positive at their first antenatal visit, but there is …

Selective transmission of CCR5-utilizing HIV-1: the'gatekeeper'problem resolved?

L Margolis, R Shattock - Nature Reviews Microbiology, 2006 - nature.com
Understanding the mechanisms of HIV-1 transmission is crucial for the development of
effective preventive microbicides and vaccine strategies, and remains one of the main goals …

[HTML][HTML] Viruses and human milk: transmission or protection?

R Francese, C Peila, M Donalisio, C Lamberti… - Advances in …, 2023 - Elsevier
Human milk (HM) is considered the best source of nutrition for infant growth and health. This
nourishment is unique and changes constantly during lactation to adapt to the physiological …

Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding

SM Graham, SE Holte, NM Peshu, BA Richardson… - Aids, 2007 - journals.lww.com
Background: Antiretroviral therapy (ART) may decrease HIV-1 infectivity in women by
reducing genital HIV-1 shedding. Objectives: To evaluate the time course and magnitude of …

Biological mechanisms of vertical human immunodeficiency virus (HIV‐1) transmission

DA Lehman, C Farquhar - Reviews in medical virology, 2007 - Wiley Online Library
In the absence of interventions, 30–45% of exposed infants acquire human
immunodeficiency virus type 1 (HIV‐1) through mother‐to‐child transmission. It remains …

Chronic HIV-1 infection frequently fails to protect against superinfection

A Piantadosi, B Chohan, V Chohan… - PLoS …, 2007 - journals.plos.org
Reports of HIV-1 superinfection (re-infection) have demonstrated that the immune response
generated against one strain of HIV-1 does not always protect against other strains …

Breastfeeding behaviors and the innate immune system of human milk: working together to protect infants against inflammation, HIV-1, and other infections

BM Henrick, XD Yao, L Nasser… - Frontiers in …, 2017 - frontiersin.org
The majority of infants' breastfeeding from their HIV-infected mothers do not acquire HIV-1
infection despite exposure to cell-free virus and cell-associated virus in HIV-infected breast …