Human papillomavirus molecular biology and disease association

J Doorbar, N Egawa, H Griffin… - Reviews in medical …, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

Adenoviral vector-based vaccine platform for COVID-19: Current status

VP Chavda, R Bezbaruah, D Valu, B Patel, A Kumar… - Vaccines, 2023 - mdpi.com
The coronavirus disease (COVID-19) breakout had an unimaginable worldwide effect in the
21st century, claiming millions of lives and putting a huge burden on the global economy …

The biology and life-cycle of human papillomaviruses

J Doorbar, W Quint, L Banks, IG Bravo, M Stoler… - Vaccine, 2012 - Elsevier
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …

Human papillomaviruses as infectious agents in gynecological cancers. Oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

Molecular biology of human papillomavirus infection and cervical cancer

J Doorbar - Clinical science, 2006 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and cause a variety of lesions ranging
from common warts/verrucas to cervical neoplasia and cancer. Over 100 different HPV types …

[HTML][HTML] The E4 protein; structure, function and patterns of expression

J Doorbar - Virology, 2013 - Elsevier
The papillomavirus E4 open reading frame (ORF) is contained within the E2 ORF, with the
primary E4 gene-product (E1∧ E4) being translated from a spliced mRNA that includes the …

Persistence of human papillomavirus infection: keys to malignant progression

J Bodily, LA Laimins - Trends in microbiology, 2011 - cell.com
Human papillomaviruses (HPVs) are the etiologic agents of cervical and other epithelial
cancers. Persistence of infections by high-risk HPV types is the single greatest risk factor for …

Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity

CM Hebner, LA Laimins - Reviews in medical virology, 2006 - Wiley Online Library
Human papillomaviruses (HPVs) are small double‐stranded DNA viruses that infect the
cutaneous and mucosal epithelium. Infection by specific HPV types has been linked to the …

Structural disorder in viral proteins

B Xue, D Blocquel, J Habchi, AV Uversky… - Chemical …, 2014 - ACS Publications
One of the core standards of biochemistry is that the function of a protein relies on its 3D
structure. This idea posits that all the information required for a protein to perform its …

Productive lifecycle of human papillomaviruses that depends upon squamous epithelial differentiation

N Kajitani, A Satsuka, A Kawate, H Sakai - Frontiers in microbiology, 2012 - frontiersin.org
Human papillomaviruses (HPVs) target the stratified epidermis, and can causes diseases
ranging from benign condylomas to malignant tumors. Infections of HPVs in the genital tract …