Reactive astrocyte nomenclature, definitions, and future directions
Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …
Astrocytes in human central nervous system diseases: a frontier for new therapies
A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
The role of astrocytes in CNS inflammation
F Giovannoni, FJ Quintana - Trends in immunology, 2020 - cell.com
Astrocytes are the most abundant cell type in the central nervous system (CNS), performing
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …
Beyond the GFAP-astrocyte protein markers in the brain
AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …
we all are aware that neurons and neuroglia are team players and constant communication …
Astrocytes: a central element in neurological diseases
The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …
primary component in the pathogenesis of neurological diseases. As this concept is …
Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system
Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …
Astrocyte reactivity and reactive astrogliosis: costs and benefits
Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
The dual role of astrocyte activation and reactive gliosis
Astrocyte activation and reactive gliosis accompany most of the pathologies in the brain,
spinal cord, and retina. Reactive gliosis has been described as constitutive, graded, multi …
spinal cord, and retina. Reactive gliosis has been described as constitutive, graded, multi …
Tropism of SARS-CoV-2 for human cortical astrocytes
MG Andrews, T Mukhtar, UC Eze… - Proceedings of the …, 2022 - National Acad Sciences
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) readily infects a variety
of cell types impacting the function of vital organ systems, with particularly severe impact on …
of cell types impacting the function of vital organ systems, with particularly severe impact on …
[HTML][HTML] Reactive gliosis in the pathogenesis of CNS diseases
Astrocytes maintain the homeostasis of the central nervous system (CNS) by eg recycling of
neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …
neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …