Vascularization and angiogenesis in tissue engineering: beyond creating static networks
J Rouwkema, A Khademhosseini - Trends in biotechnology, 2016 - cell.com
Engineered tissues need a vascular network to supply cells with nutrients and oxygen after
implantation. A network that can connect to the vasculature of the patient after implantation …
implantation. A network that can connect to the vasculature of the patient after implantation …
Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
3D printing of microgel scaffolds with tunable void fraction to promote cell infiltration
AJ Seymour, S Shin… - Advanced healthcare …, 2021 - Wiley Online Library
Granular, microgel‐based materials have garnered interest as promising tissue engineering
scaffolds due to their inherent porosity, which can promote cell infiltration. Adapting these …
scaffolds due to their inherent porosity, which can promote cell infiltration. Adapting these …
Collective cell migration: guidance principles and hierarchies
Collective cell migration results from the establishment and maintenance of collective
polarization, mechanocoupling, and cytoskeletal kinetics. The guidance of collective cell …
polarization, mechanocoupling, and cytoskeletal kinetics. The guidance of collective cell …
Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
This protocol describes a simple but robust microfluidic assay combining three-dimensional
(3D) and two-dimensional (2D) cell culture. The microfluidic platform comprises hydrogel …
(3D) and two-dimensional (2D) cell culture. The microfluidic platform comprises hydrogel …
3D microvascularized tissue models by laser‐based cavitation molding of collagen
Abstract 3D tissue models recapitulating human physiology are important for fundamental
biomedical research, and they hold promise to become a new tool in drug development. An …
biomedical research, and they hold promise to become a new tool in drug development. An …
Generation of multi-scale vascular network system within 3D hydrogel using 3D bio-printing technology
Although 3D bio-printing technology has great potential in creating complex tissues with
multiple cell types and matrices, maintaining the viability of thick tissue construct for tissue …
multiple cell types and matrices, maintaining the viability of thick tissue construct for tissue …
Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases
V Paloschi, M Sabater-Lleal… - Cardiovascular …, 2021 - academic.oup.com
The development of organs-on-chip (OoC) has revolutionized in vitro cell-culture
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
Coaxial cell printing of freestanding, perfusable, and functional in vitro vascular models for recapitulation of native vascular endothelium pathophysiology
Abstract 3D printing technology is used to produce channels within hydrogels followed by
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …
Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment
Cancer remains one of the leading causes of death, albeit enormous efforts to cure the
disease. To overcome the major challenges in cancer therapy, we need to have a better …
disease. To overcome the major challenges in cancer therapy, we need to have a better …