Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

Systemic lupus erythematosus and cardiovascular disease

J Frostegård - Journal of Internal Medicine, 2023 - Wiley Online Library
The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis–novel insights and future directions in diagnosis and therapy

A Hartley, D Haskard, R Khamis - Trends in Cardiovascular Medicine, 2019 - Elsevier
We provide an up-to-date overview of current topics surrounding oxidized low-density
lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at …

Hypertension: focus on autoimmunity and oxidative stress

HY Small, S Migliarino, M Czesnikiewicz-Guzik… - Free Radical Biology …, 2018 - Elsevier
Understanding the causal role of the immune and inflammatory responses in hypertension
has led to questions regarding the links between hypertension and autoimmunity. Immune …

Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies

F Porsch, Z Mallat, CJ Binder - Cardiovascular research, 2021 - academic.oup.com
Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …

[HTML][HTML] Combined multimorbidity and polypharmacy patterns in the elderly: a cross-sectional study in primary health care

G Stafford, N Villén, A Roso-Llorach… - International journal of …, 2021 - mdpi.com
(1) Background: The acquisition of multiple chronic diseases, known as multimorbidity, is
common in the elderly population, and it is often treated with the simultaneous consumption …

Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms

T Kyaw, P Loveland, P Kanellakis, A Cao… - European heart …, 2021 - academic.oup.com
Aims Myocardial infarction (MI) accelerates atherosclerosis and greatly increases the risk of
recurrent cardiovascular events for many years, in particular, strokes and MIs. Because B …

Vaccination against atherosclerosis

K Kobiyama, R Saigusa, K Ley - Current opinion in immunology, 2019 - Elsevier
Highlights•Antibody-inducing vaccines against atherosclerosis are designed to induce
neutralizing antibodies.•Treg-inducing vaccines against atherosclerosis are designed to …

Vaccination strategies and immune modulation of atherosclerosis

J Nilsson, GK Hansson - Circulation Research, 2020 - Am Heart Assoc
Adaptive as well as innate immune responses contribute to the development of
atherosclerosis. Studies performed in experimental animals have revealed that some of …