[HTML][HTML] Energy metabolism changes and dysregulated lipid metabolism in postmenopausal women

SH Ko, YJ Jung - Nutrients, 2021 - mdpi.com
Aging women experience hormonal changes, such as decreased estrogen and increased
circulating androgen, due to natural or surgical menopause. These hormonal changes make …

Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders

WS Blaner - Pharmacology & therapeutics, 2019 - Elsevier
Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Retinoic acid receptors: from molecular mechanisms to cancer therapy

A Di Masi, L Leboffe, E De Marinis, F Pagano… - Molecular aspects of …, 2015 - Elsevier
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

[HTML][HTML] Chemistry of the retinoid (visual) cycle

PD Kiser, M Golczak, K Palczewski - Chemical reviews, 2014 - ACS Publications
As succinctly summarized by Wolf, 1 lack of vitamin A (all-trans-retinol) was recognized by
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …

[HTML][HTML] Retinol and retinyl esters: biochemistry and physiology: thematic review series: fat-soluble vitamins: vitamin A

SM O'Byrne, WS Blaner - Journal of lipid research, 2013 - ASBMB
By definition, a vitamin is a substance that must be obtained regularly from the diet. Vitamin
A must be acquired from the diet, but unlike most vitamins, it can also be stored within the …

Mechanistic aspects of carotenoid biosynthesis

AR Moise, S Al-Babili, ET Wurtzel - Chemical reviews, 2014 - ACS Publications
Carotenoids represent a large class of terpenoids characterized by an extensively
conjugated polyene chain. The conjugation system imparts carotenoids with excellent light …

Functions, therapeutic applications, and synthesis of retinoids and carotenoids

R Alvarez, B Vaz, H Gronemeyer, AR de Lera - Chemical reviews, 2014 - ACS Publications
Vitamin A (all-trans-retinol, 1, Figure 1) is considered the most multifunctional vitamin in the
human body. 1 It plays key roles in many physiological processes such as vision …

β-Carotene in the human body: metabolic bioactivation pathways–from digestion to tissue distribution and excretion

T Bohn, C Desmarchelier, SN El, J Keijer… - Proceedings of the …, 2019 - cambridge.org
β-Carotene intake and tissue/blood concentrations have been associated with reduced
incidence of several chronic diseases. Further bioactive carotenoid-metabolites can …

An unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin

T Cao, Y Bai, P Buschbeck, Q Tan, MB Cantrell… - The Plant …, 2023 - academic.oup.com
The ketocarotenoid fucoxanthin and its derivatives can absorb blue–green light enriched in
marine environments. Fucoxanthin is widely adopted by phytoplankton species as a main …