Genetic landscape and biomarkers of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …
mortality has increased in Western populations, with a minority of patients diagnosed at …
Insulin-like growth factor (IGF) system in liver diseases
A Adamek, A Kasprzak - International journal of molecular sciences, 2018 - mdpi.com
Hepatocyte differentiation, proliferation, and apoptosis are affected by growth factors
produced in liver. Insulin-like growth factor 1 and 2 (IGF1 and IGF2) act in response to …
produced in liver. Insulin-like growth factor 1 and 2 (IGF1 and IGF2) act in response to …
Deep learning–based multi-omics integration robustly predicts survival in liver cancer
Identifying robust survival subgroups of hepatocellular carcinoma (HCC) will significantly
improve patient care. Currently, endeavor of integrating multi-omics data to explicitly predict …
improve patient care. Currently, endeavor of integrating multi-omics data to explicitly predict …
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
HB El–Serag, KL Rudolph - Gastroenterology, 2007 - Elsevier
Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is
the fifth most common cancer worldwide and the third most common cause of cancer …
the fifth most common cancer worldwide and the third most common cause of cancer …
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to
develop genomic-based classification for HCC have yielded highly divergent results …
develop genomic-based classification for HCC have yielded highly divergent results …
Liver cancer: approaching a personalized care
The knowledge and understanding of all aspects of liver cancer [this including
hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA)] have …
hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA)] have …
[PDF][PDF] Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
S Boyault, DS Rickman, A De Reyniès… - …, 2007 - Wiley Online Library
Hepatocellular carcinomas (HCCs) are a heterogeneous group of tumors that differ in risk
factors and genetic alterations. We further investigated transcriptome‐genotype‐phenotype …
factors and genetic alterations. We further investigated transcriptome‐genotype‐phenotype …
[HTML][HTML] Targeting the insulin-like growth factor pathway in hepatocellular carcinoma
M Enguita-Germán, P Fortes - World journal of hepatology, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide. Only 30%-40% of the patients with HCC are eligible for curative treatments …
worldwide. Only 30%-40% of the patients with HCC are eligible for curative treatments …
[PDF][PDF] Molecular targeted therapies in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with several
genomic alterations. There is evidence of aberrant activation of several signaling cascades …
genomic alterations. There is evidence of aberrant activation of several signaling cascades …
Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma
Hepatocellular carcinomas represent the third leading cause of cancer-related deaths
worldwide. The vast majority of cases arise in the context of chronic liver injury due to …
worldwide. The vast majority of cases arise in the context of chronic liver injury due to …