Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Mild-to-moderate traumatic brain injury: a review with focus on the visual system

SH Rauchman, J Albert, A Pinkhasov, AB Reiss - Neurology International, 2022 - mdpi.com
Traumatic Brain Injury (TBI) is a major global public health problem. Neurological damage
from TBI may be mild, moderate, or severe and occurs both immediately at the time of impact …

Oxidative stress in the brain and retina after traumatic injury

AK Ryan, W Rich, MA Reilly - Frontiers in neuroscience, 2023 - frontiersin.org
The brain and the retina share many physiological similarities, which allows the retina to
serve as a model of CNS disease and disorder. In instances of trauma, the eye can even …

Biomechanical analysis of ocular diseases and its in vitro study methods

Y Zhao, G Hu, Y Yan, Z Wang, X Liu, H Shi - BioMedical Engineering …, 2022 - Springer
Ocular diseases are closely related to the physiological changes in the eye sphere and its
contents. Using biomechanical methods to explore the relationship between the structure …

Biomechanics of open-globe injury: a review

S Wang, F Li, S Jin, Y Zhang, N Yang… - Biomedical engineering …, 2023 - Springer
Open-globe injury is a common cause of blindness clinically caused by blunt trauma, sharp
injury, or shock waves, characterised by rupture of the cornea or sclera and exposure of eye …

Diffusion basis spectrum imaging detects subclinical traumatic optic neuropathy in a closed-head impact mouse model of traumatic brain injury

HC Yang, RS Lavadi, AD Sauerbeck… - Frontiers in …, 2023 - frontiersin.org
Introduction Traumatic optic neuropathy (TON) is the optic nerve injury secondary to brain
trauma leading to visual impairment and vision loss. Current clinical visual function …

Displacement voxelization to resolve mesh-image mismatch: application in deriving dense white matter fiber strains

S Ji, W Zhao - Computer methods and programs in biomedicine, 2022 - Elsevier
Background and objective It is common to combine biomechanical modeling and medical
images for multimodal analyses. However, mesh-image mismatch may occur that prevents …

有限元方法在脑震荡领域的热点: 脑损伤模型, 测试方法与防护装备的改进

罗卫东, 邹丽华, 黄达 - 中国组织工程研究, 2024 - cjter.com
有限元方法在脑震荡领域的热点:脑损伤模型,测试方法与防护装备的改进 Page 1 Chinese
Journal of Tissue Engineering Research|Vol 28|No.34|December 2024|5487 中国组织工程 …

Linear viscoelasticity of human sclera and posterior ocular tissues during tensile creep

D Song, S Lim, J Park, JL Demer - Journal of Biomechanics, 2023 - Elsevier
Purpose Despite presumed relevance to ocular diseases, the viscoelastic properties of the
posterior human eye have not been evaluated in detail. We performed creep testing to …

Quantitative assessment of brain injury and concussion induced by an unintentional soccer ball impact

Y Cao, Y Liu, L Tang, Z Jiang, Z Liu, L Zhou, B Yang - Injury, 2024 - Elsevier
Background: Accidental impact on a player's head by a powerful soccer ball may lead to
brain injuries and concussions during games. It is crucial to assess these injuries promptly …