Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …

Tumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …

Acute inflammatory responses are protective, yet without timely resolution can lead to
chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self …

Guidelines for clinical practice are aimed to indicate preferred approaches to medical
problems as established by scientifically valid research. Double-blind placebo controlled …

Stimulation and release of proinflammatory cytokines is an essential step for the activation of
an effective innate host defense, and subsequently for the modulation of adaptive immune …

Implantable medical devices have revolutionized modern medicine. However, immune-
mediated foreign body response (FBR) to the materials of these devices can limit their …

Current therapies for asthma and allergy are relatively safe and effective at controlling
symptoms but do not change the chronic course of disease. There is no established method …

Abstract Introduction: Interleukin 17 (IL-17) antagonism provides a highly effective approach
for treating psoriasis. Exacerbations of inflammatory bowel disease have been reported in …

Signaling pathways induced by the proinflammatory cytokine tumor necrosis factor alpha
(TNF-α) play a key role in the cellular responses to inflammation and injury. In the …

Diabetes and hyperglycemia create a proinflammatory microenvironment that progresses to
microvascular complications such as nephropathy, retinopathy, and neuropathy. Diet …