The role of blood rheology in sickle cell disease
Studies performed in the last decades have highlighted the need to better understand the
contribution of the endothelium, vascular function, oxidative stress, inflammation …
contribution of the endothelium, vascular function, oxidative stress, inflammation …
The role of leukotrienes in immunopathogenesis of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disorder of joints for which there is no
strict cure. However, conventional medications can reduce inflammation, relieve pain, and …
strict cure. However, conventional medications can reduce inflammation, relieve pain, and …
[HTML][HTML] Eicosanoid pathway on host resistance and inflammation during Mycobacterium tuberculosis infection is comprised by LTB4 reduction but not PGE2 …
The functions of eicosanoids, a family of potent biologically active lipid mediators, are not
restricted to inflammatory responses and they also act as mediators of the pathogenesis …
restricted to inflammatory responses and they also act as mediators of the pathogenesis …
The inhibition of 5-Lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves …
FR Guimaraes, H Sales-Campos, V Nardini… - Clinical …, 2018 - Elsevier
To analyze the participation of the enzyme 5-lipoxygenase (5-LO) in skin repair, WT wounds
were compared to those in 5-LO deficient mice (5-LO−/−), which presented faster closure …
were compared to those in 5-LO deficient mice (5-LO−/−), which presented faster closure …
[HTML][HTML] Spirulina polysaccharide induces the metabolic shifts and gut microbiota change of lung cancer in mice
Y Lu, B Peng, Y Lin, Q Lin, X Xia, S Zhong, L Luo… - Current Research in …, 2022 - Elsevier
A polysaccharide obtained from Spirulina (PSP) and its effect on lung cancer in mice was
investigated. Our results indicate that the tumor volume and weight of the lung cancer …
investigated. Our results indicate that the tumor volume and weight of the lung cancer …
Therapeutic potential of biodegradable microparticles containing Punica granatum L. (pomegranate) in murine model of asthma
JFF de Oliveira, DV Garreto, MCP da Silva… - Inflammation …, 2013 - Springer
Objective and design Among the options for treatment of diseases affecting the respiratory
system, especially asthma, drug delivering systems for intranasal application represent an …
system, especially asthma, drug delivering systems for intranasal application represent an …
20-Hydroxy- and 20-carboxy-leukotriene (LT) B4 downregulate LTB4-mediated responses of human neutrophils and eosinophils
AS Archambault, S Poirier, JS Lefebvre… - Journal of Leukocyte …, 2019 - academic.oup.com
Abstract Leukotriene B4 (LTB4) plays a prominent role in innate immunity as it induces
phagocyte recruitment, the release of antimicrobial effectors, and as it potentiates the …
phagocyte recruitment, the release of antimicrobial effectors, and as it potentiates the …
Antileishmanial and Immunomodulatory Effect of Babassu‐Loaded PLGA Microparticles: A Useful Drug Target to Leishmania amazonensis Infection
The immunological and the anti-Leishmania amazonensis activity of babassu‐loaded poly
(lactic‐co‐glycolic acid)[PLGA] microparticles was evaluated. The anti‐Leishmania activity …
(lactic‐co‐glycolic acid)[PLGA] microparticles was evaluated. The anti‐Leishmania activity …
Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis
A Mirshafiey, F Jadidi-Niaragh - Immunopharmacology and …, 2010 - Taylor & Francis
Background and aim: Multiple sclerosis (MS) is a chronic inflammatory disease that involves
central nervous system, and is generally associated with demyelination and axonal lesion …
central nervous system, and is generally associated with demyelination and axonal lesion …
Pulmonary drug delivery system: a novel approach for drug delivery
A Singh, R Malviya, P K. Sharma - Current Drug Therapy, 2011 - benthamdirect.com
In present study authors review all aspects of pulmonary drug delivery system; including
need of drug delivery, different approaches for drug delivery and recent advancement in …
need of drug delivery, different approaches for drug delivery and recent advancement in …