Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

Background: Inflammation is a part of the first line of defense of the body against invasive
pathogens, and plays a crucial role in tissue regeneration and repair. A proper inflammatory …

Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders,
such as Parkinson's disease, amyotrophic lateral sclerosis, and depression. However …

Although the potential contribution of the human gastrointestinal (GI) tract microbiome to
human health, aging, and disease is becoming increasingly acknowledged, the molecular …

Women and men are suggested to have differences in vulnerability to neuropsychiatric
disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD) …

In the past decade, numerous studies have demonstrated the close relationship between gut
microbiota and the occurrence and development of Alzheimer's disease (AD). However, the …

The human microbiome consists of~ 3.8× 1013 symbiotic microorganisms that form a highly
complex and dynamic ecosystem: the gastrointestinal (GI) tract constitutes the largest …

Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

The characteristic maximum lifespan varies enormously across animal species from a few
hours to hundreds of years. This argues that maximum lifespan, and the ageing process that …