The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

INTRODUCTION Vision provides a critical survival advantage but requires a tight coupling
between neuronal energy demands and their vascular supply. The degeneration and …

Attenuating pathological angiogenesis in diseases characterized by neovascularization
such as diabetic retinopathy has transformed standards of care. Yet little is known about the …

Pathological angiogenesis is the hallmark of diseases such as cancer and retinopathies.
Although tissue hypoxia and inflammation are recognized as central drivers of vessel …

Tissues with high metabolic rates often use lipids, as well as glucose, for energy, conferring
a survival advantage during feast and famine. Current dogma suggests that high-energy …

Pathological angiogenesis in the eye is an important feature in the pathophysiology of many
vision-threatening diseases, including retinopathy of prematurity, diabetic retinopathy, and …

This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …

Retinopathy of prematurity (ROP) is a major complication of preterm birth. It encompasses a
spectrum of pathologies that affect vision, from mild disease that resolves spontaneously to …

Lipid signaling is dysregulated in many diseases with vascular pathology, including cancer,
diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration. We …