Immunosuppressive mechanisms of regulatory B cells
D Catalán, MA Mansilla, A Ferrier, L Soto… - Frontiers in …, 2021 - frontiersin.org
Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
Human regulatory B cells in health and disease: therapeutic potential
C Mauri, M Menon - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Regulatory B cells (Bregs) modulate immune responses predominantly, although not
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …
B cells in the tumor microenvironment: Multi-faceted organizers, regulators, and effectors of anti-tumor immunity
CM Laumont, BH Nelson - Cancer Cell, 2023 - cell.com
Our understanding of tumor-infiltrating lymphocytes (TILs) is rapidly expanding beyond T cell-
centric perspectives to include B cells and plasma cells, collectively referred to as TIL-Bs. In …
centric perspectives to include B cells and plasma cells, collectively referred to as TIL-Bs. In …
The expanding family of regulatory B cells
C Mauri, M Menon - International immunology, 2015 - academic.oup.com
Over the last decade it has become evident that in addition to producing antibody, B cells
activate the immune system by producing cytokines and via antigen presentation. In …
activate the immune system by producing cytokines and via antigen presentation. In …
B cell orchestration of anti-tumor immune responses: a matter of cell localization and communication
The immune system plays a crucial role in cancer development either by fostering tumor
growth or destroying tumor cells, which has open new avenues for cancer immunotherapy. It …
growth or destroying tumor cells, which has open new avenues for cancer immunotherapy. It …
The emerging role of regulatory cell-based therapy in autoimmune disease
F Ghobadinezhad, N Ebrahimi, F Mozaffari… - Frontiers in …, 2022 - frontiersin.org
Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …
millions of people each year and poses a great social and economic burden to individuals …
Role of indoleamine 2, 3-dioxygenase in health and disease
IDO1 (indoleamine 2, 3-dioxygenase 1) is a member of a unique class of mammalian haem
dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino …
dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino …
Role of transforming growth factor-β1 in regulating fetal-maternal immune tolerance in normal and pathological pregnancy
D Yang, F Dai, M Yuan, Y Zheng, S Liu… - Frontiers in …, 2021 - frontiersin.org
Transforming growth factor-β (TGF-β) is composed of three isoforms, TGF-β1, TGF-β2, and
TGF-β3. TGF-β1 is a cytokine with multiple biological functions that has been studied …
TGF-β3. TGF-β1 is a cytokine with multiple biological functions that has been studied …
The role of regulatory B cells in health and diseases: a systemic review
E Chekol Abebe, T Asmamaw Dejenie… - Journal of …, 2021 - Taylor & Francis
Equivalent to regulatory T cells, a novel B cell populace, called regulatory B cells (Bregs),
has been found to exert a negative immune regulatory role. These subsets of cells account …
has been found to exert a negative immune regulatory role. These subsets of cells account …