[HTML][HTML] Behçet's syndrome patients exhibit specific microbiome signature

C Consolandi, S Turroni, G Emmi, M Severgnini… - Autoimmunity …, 2015 - Elsevier
Background and aims Behçet syndrome is a systemic inflammatory condition characterized
by muco-cutaneous and ocular manifestations, with central nervous system, vascular and/or …

New insights into the pathogenesis of Behcet's disease

MP de Chambrun, B Wechsler, G Geri, P Cacoub… - Autoimmunity …, 2012 - Elsevier
Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of …

Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome

H Konaka, Y Kato, T Hirano, K Tsujimoto… - The EMBO …, 2023 - embopress.org
Mitochondrial DNA (mtDNA) leakage into the cytoplasm can occur when cells are exposed
to noxious stimuli. Specific sensors recognize cytoplasmic mtDNA to promote cytokine …

[HTML][HTML] Immunopathogenesis of Behçet's disease and treatment modalities

TB Van der Houwen, PM van Hagen… - Seminars in Arthritis and …, 2022 - Elsevier
Introduction Behçet's disease (BD) is an auto-inflammatory disease, primarily characterized
by recurrent painful mucocutaneous ulcerations. Methods A literature search was performed …

Sequencing of 16S rRNA reveals a distinct salivary microbiome signature in Behcet's disease

P Coit, G Mumcu, F Ture-Ozdemir, AU Unal, U Alpar… - Clinical …, 2016 - Elsevier
Behçet's disease (BD) is characterized by recurrent oro-genital ulcers, mucocutaneous
lesions, and serious organ involvement. We investigated the salivary microbiome in BD …

[HTML][HTML] Behcet's disease: an in-depth review about pathogenesis, gastrointestinal manifestations, and management

A Nguyen, S Upadhyay, MA Javaid… - Inflammatory Intestinal …, 2021 - karger.com
Background: Behcet's disease (BD) is a complex inflammatory vascular disorder that follows
a relapsing-remitting course with diverse clinical manifestations. The prevalence of the …

Behcet's disease under microbiotic surveillance? A combined analysis of two cohorts of Behcet's disease patients

TB Van der Houwen, JAM Van Laar… - Frontiers in …, 2020 - frontiersin.org
Background: In Behçet's disease (BD), an auto-inflammatory vasculitis, an unbalanced gut
microbiota can contribute to pro-inflammatory reactions. In separate studies, distinct pro-and …

Triggering agents and microbiome as environmental factors on Behçet's syndrome

G Mumcu, H Direskeneli - Internal and Emergency Medicine, 2019 - Springer
Environmental and other triggering factors are suggested to cause the onset and the clinical
relapses of Behçet's syndrome (BS), a multi-systemic inflammatory disorder. In this review …

Behçet syndrome: from pathogenesis to novel therapies

G Mazzoccoli, A Matarangolo, R Rubino… - Clinical and …, 2016 - Springer
Behçet syndrome is a chronic disease hallmarked by inflammation of the blood vessels that
is related to an autoimmune reaction caused by inherited susceptibility due to specific genes …

The role of bacteria and viruses in Behçet syndrome: Should we move towards new paradigms?

S Sciascia, M Arbrile, M Trunfio, A Calcagno… - Autoimmunity …, 2023 - Elsevier
The etiological complexity of Behçet syndrome (BS), an immune-mediated rare form of
vasculitis characterized by multi-organ involvement, is still elusive due to an incomplete …