Gastrointestinal functions after laparoscopic right colectomy with intracorporeal anastomosis: a pilot randomized clinical trial on effects of abdominal drain, prolonged …

GS Sica, L Siragusa, BM Pirozzi, R Sorge… - International Journal of …, 2024 - Springer
Purpose Routine use of abdominal drain or prolonged antibiotic prophylaxis is no longer
part of current clinical practice in colorectal surgery. Nevertheless, in patients undergoing …

Development of a core descriptor set for Crohn's anal fistula

ENiGMA CODE Collaborators, KM Williams… - Colorectal …, 2023 - Wiley Online Library
Aim Crohn's anal fistula (CAF) is a complex condition, with no agreement on which patient
characteristics should be routinely reported in studies. The aim of this study was to develop …

Formation of a conceptual framework during the development of a patient‐reported outcome measure for early gastrointestinal recovery: phase I of the PRO‐diGi study

DM Baker, SJ Chapman, BD Thomas… - Colorectal …, 2023 - Wiley Online Library
Aim Patients admitted to hospital for abdominal surgery often experience gastrointestinal
dysfunction. Many studies have reported outcomes following gastrointestinal dysfunction, yet …

Non‐invasive vagus nerve stimulation to reduce ileus after colorectal surgery: randomized feasibility trial and efficacy assessment (IDEAL Stage 2B)

SJ Chapman, M Kowal, JA Helliwell… - Colorectal …, 2024 - Wiley Online Library
Aim Ileus is characterized by a period of intestinal dysmotility after surgery, leading to
vomiting and constipation. In preclinical models, vagus nerve stimulation reduces intestinal …

Docosahexaenoic acid (DHA) promotes recovery from postoperative ileus and the repair of the injured intestinal barrier through mast cell-nerve crosstalk

K Yi, L An, Y Qi, T Yang, Y Duan, X Zhao… - International …, 2024 - Elsevier
The objective of this study was to investigate the neuroimmune mechanisms implicated in
the enhancement of gastrointestinal function through the administration of oral DHA. Mast …

Electroacupuncture promotes gastrointestinal functional recovery after radical colorectal cancer surgery: a protocol of multicenter randomized controlled trial …

L Sun, X Wei, T Feng, Q Gu, J Li, K Wang… - International Journal of …, 2024 - Springer
Methods This study is a multicenter, parallel-group, randomized controlled trial, named as
CORRECT. CORRECT trial will recruit 300 participants diagnosed with colorectal cancer …

Prophylactic Intra-abdominal Drainage is Associated With Lower Postoperative Complications in Patients With Crohn's Disease: A Randomized Controlled Trial

M Duan, L Cao, M Lu, T Zhang, Q Ji, X Guo… - Surgical …, 2024 - journals.sagepub.com
Background Prophylactic intraoperative drains have been shown not superior for patients
underwent intestinal surgery. However, for patients with Crohn's disease (CD), this needs …

Effect of chewing gum on duration of postoperative ileus following laparotomy for gastroduodenal perforations: protocol for a randomized controlled trial

J Muhumuza, SF Molen, W Mauricio… - … Journal of Surgery …, 2023 - journals.lww.com
Background: Prolonged post-operative ileus is associated with increased risk of other
complications, length of hospital stays and health care related costs. Chewing gum has …

Pyridostigmine to Reduce the duration of postoperative Ileus after Colorectal surgery (PyRICo-RCT): randomized clinical trial

L Traeger, S Bedrikovetski, T Fitzsimmons… - British Journal of …, 2024 - academic.oup.com
Background Postoperative ileus, driven by the cholinergic anti-inflammatory pathway, is the
most common complication in patients undergoing colorectal surgery. By inhibiting …

Predictive modeling of postoperative gastrointestinal dysfunction: the role of serum bilirubin, sodium levels, and surgical duration in gynecological cancer care

L He, J Hu, Y Han, W Xiong - BMC Women's Health, 2023 - Springer
Objective To elucidate the role of preoperative serum bilirubin and sodium levels, along with
the duration of surgery, in predicting postoperative gastrointestinal dysfunction (POGD) …