Epigenetic reprogramming during the maternal‐to‐zygotic transition

Y Chen, L Wang, F Guo, X Dai, X Zhang - MedComm, 2023 - Wiley Online Library
After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of
a new life. Then the embryonic development is monitored and regulated precisely from the …

Reactive oxygen species signalling in the deterioration of quality of mammalian oocytes cultured in vitro: Protective effect of antioxidants

AN Pandey, PK Yadav, KV Premkumar, M Tiwari… - Cellular …, 2024 - Elsevier
The in vitro fertilization (IVF) is the first choice of infertile couples worldwide to plan for
conception. Besides having a significant advancement in IVF procedure, the success rate is …

Adverse effects of 2-methoxyestradiol on mouse oocytes during reproductive aging

X Jiang, X Xu, B Wang, K Song, J Zhang… - Chemico-Biological …, 2023 - Elsevier
Methoxyestradiol (2-ME2) is a metabolite of 17β-estradiol and is currently in clinical trials as
an antitumor agent. Here we found 2-ME2 level remains stable in the local environment of …

Calcium signaling in oocyte quality and functionality and its application

C Chen, Z Huang, S Dong, M Ding, J Li… - Frontiers in …, 2024 - frontiersin.org
Calcium (Ca2+) is a second messenger for many signal pathways, and changes in
intracellular Ca2+ concentration ([Ca2+] i) are an important signaling mechanism in the …

Follicular oocyte as a potential target for severe acute respiratory syndrome coronavirus 2 infection

PK Yadav, AN Pandey, KV Premkumar… - Reviews in Medical …, 2024 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was reported in
December 2019 and rapidly became a pandemic as coronavirus disease 2019 (COVID‐19) …

Oocyte spontaneous activation: an overlooked cellular event that impairs female fertility in mammals

W Cui - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
In mammals, including humans, mature oocytes are ovulated into the oviduct for fertilization.
Normally, these oocytes are arrested at metaphase of the second meiosis (MII), and this …