Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …

Apoptosis is the term given to programmed cell death, which has been widely connected to
a number of intracranial pathologies including stroke, Alzheimer's disease, and more …

Subarachnoidal release of inflammatory cytokines (interleukin (IL)-1β, IL-6, and tumour
necrosis factor (TNF)-α) was characterised in 35 patients with subarachnoid haemorrhage …

Background and Purpose—Despite recent advances in the treatment of patients after
subarachnoid hemorrhage, morbidity and mortality rates have failed to improve significantly …

Objectives: Increasing body of experimental and clinical data indicates that early brain injury
after initial bleeding largely contributes to unfavorable outcome after subarachnoid …

[Frontiers in Bioscience 16, 1733-1745, January 1, 2011] 1733 Oxidative stress and endothelial
dysfunction in cerebrovascular di Page 1 [Frontiers in Bioscience 16, 1733-1745, January 1 …

Aneurysmal subarachnoid hemorrhage frequently results in complications including
intracranial hypertension, rebleeding and vasospasm. The extravasated blood is …

Until the 1970s, reactive oxygen species (ROS) were considered merely harmful by-
products of aerobic respiration and the driving force behind the evolution of an array of …

Brain injury after subarachnoid hemorrhage (SAH) is a biphasic event with an acute
ischemic insult at the time of the initial bleed and secondary events such as cerebral …