Methods: We searched in PubMed and Web of Science (up to January 10, 2018) for genetic
studies of POAG. All case control studies investigating the association between single …

Glaucoma is a neurodegenerative disease and one of the leading causes of irreversible
blindness, affecting over 60 million people worldwide. At the present time, glaucoma is …

Purpose Glaucoma is a common disease often identified by high intraocular pressure,
characteristic optic neuropathy and vision loss. It is currently a leading cause of blindness …

Topic Systematic review and meta-analysis of the genetic associations of primary angle-
closure disease (PACD). Clinical Relevance To confirm the genetic biomarkers for PACD …

Purpose. We investigated the association between genotypes and haplotypes of the c.‐
61G> T (rs 1801320) and c.‐98G> C (rs 1801321) polymorphisms of the RAD51 gene and …

Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by irreversible
retinal ganglion cell damage and visual field loss. The global POAG prevalence is estimated …

BACKGROUND: Numerous data have shown that progressive loss of human trabecular
meshwork (TM) cells may be connected with oxidative stress. This hypothesis may suggest …

Keratoconus (KC) is a degenerative corneal disorder for which the exact pathogenesis is not
yet known. Oxidative stress is reported to be associated with this disease. The stress may …

Objective This meta-analysis aimed to determine the relationships between XRCC1
Arg399Gln (rs25487 G> A) and XPD Lys751Gln (rs1052559 A> C) polymorphisms and …

Recently an association was observed between alleles in genes of the unfolded protein
response pathway and primary open angle glaucoma (POAG). The goal of the current study …