Immunology of aging: the birth of inflammaging
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …
evolutionary or rather a revolutionary conceptualization of the immune changes in response …
Human coronaviruses: a review of virus–host interactions
Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …
Interaction of dietary polyphenols and gut microbiota: Microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health
The human gastrointestinal tract is inhabited by a vast number of microorganisms that are
called as the microbiota. Each individual harbors a unique gut microbial composition, this …
called as the microbiota. Each individual harbors a unique gut microbial composition, this …
Middle East respiratory syndrome coronavirus (MERS‐CoV): infection, immunological response, and vaccine development
A Mubarak, W Alturaiki… - Journal of immunology …, 2019 - Wiley Online Library
Middle East respiratory syndrome coronavirus (MERS‐CoV) first emerged in late 2012.
Since its emergence, a total of 2279 patients from 27 countries have been infected across …
Since its emergence, a total of 2279 patients from 27 countries have been infected across …
The hallmarks of flavonoids in cancer
LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …
foods and beverages with known biological activity in cells. From the modulation of …
The gut microbiota, obesity and insulin resistance
J Shen, MS Obin, L Zhao - Molecular aspects of medicine, 2013 - Elsevier
The human gut is densely populated by commensal and symbiotic microbes (the “gut
microbiota”), with the majority of the constituent microorganisms being bacteria …
microbiota”), with the majority of the constituent microorganisms being bacteria …
Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk
The symbiotic gut microbiota modulate health and disease of the host through a series of
transgenomic metabolic and immune regulatory axes. We explore connections between …
transgenomic metabolic and immune regulatory axes. We explore connections between …
[HTML][HTML] PI3K inhibitors in inflammation, autoimmunity and cancer
AK Stark, S Sriskantharajah, EM Hessel… - Current opinion in …, 2015 - Elsevier
Highlights•Preclinical studies support us of PI3K inhibitors in autoimmunity and
inflammation.•First in class PI3K inhibitor has been approved for treatment of B cell …
inflammation.•First in class PI3K inhibitor has been approved for treatment of B cell …
TLR2 and TLR4 in autoimmune diseases: a comprehensive review
Y Liu, H Yin, M Zhao, Q Lu - Clinical reviews in allergy & immunology, 2014 - Springer
Autoimmune diseases are immune disorders characterized by T cell hyperactivity and B cell
overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of …
overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of …
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
RA Rosalia, LJ Cruz, S van Duikeren, AT Tromp… - Biomaterials, 2015 - Elsevier
Dendritic cells (DC) play a prominent role in the priming of CD8+ T cells. Vaccination is a
promising treatment to boost tumor-specific CD8+ T cells which is crucially dependent on …
promising treatment to boost tumor-specific CD8+ T cells which is crucially dependent on …