Although molecular approaches altering mitochondrial content have implied a direct
relationship between mitochondrial bioenergetics and insulin sensitivity, paradoxically …

Mitochondrial bioenergetic contributions to sex differences in human skeletal muscle
metabolism remain poorly defined. The primary aim of this study was to determine whether …

Objectives Patients with type 2 diabetes (T2DM) are at increased fracture risk. Resveratrol
has shown beneficial effects on bone health in few studies. The aim of this trial was to …

Down syndrome is the most common genomic disorder of intellectual disability and is
caused by trisomy of chromosome 21. Several genes in this chromosome repress …

A high-fat (HF) diet leads to detrimental effects on alveolar bone (AB); however, the
mechanisms linking adiposity to bone loss are poorly understood. This study investigated if …

Aims: High-fat diet (HFD)-induced insulin resistance (IR) impairs skeletal muscle
mitochondrial biogenesis and functions, adversely affecting human health and lifespan …

Acute exercise rapidly induces mitochondrial gene expression, however, the intracellular
events regulating this process remain incompletely understood. The purpose of this study …

Type 2 diabetes interferes with bone remodeling mechanisms, requiring studies to reverse
this damage, and resveratrol is a polyphenol with rich properties. This study aimed to …

Osteolytic bone diseases, such as osteoporosis, are characterized by diminished bone
quality and increased fracture risk. The therapeutic challenge remains to maintain bone …

Objectives The aim of the study was to investigate the effect of obesity on the tissue and
molecular reactions of alveolar bone in response to orthodontic force and its underlying …