GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Diverse computations in the neocortex are aided by specialized GABAergic interneurons
(INs), which selectively target other INs. However, much less is known about how these …

Low-dose ketamine, an open-channel N-methyl d-aspartate receptor (NMDAR) antagonist,
mediates rapid antidepressant effects in humans that are mimicked in preclinical rodent …

In this work, through a detailed literature review, data‐mining, and extensive calculations,
we provide a current, quantitative estimate of the cellular and synaptic constituents of the …

A key function of the prefrontal cortex is to support inhibitory control over behavior. It is
widely believed that this function extends to stopping cognitive processes as well …

Prefrontal cortex (PFC) is postulated to exert" top-down control" on information processing
throughout the brain to promote specific behaviors. However, pathways mediating top-down …

Recurrent excitatory connections in hippocampal regions CA3 and CA2 are thought to play
a key role in the generation of sharp-wave ripples (SWRs), electrophysiological oscillations …

The diversity of GABAA receptor (GABAAR) subunits and the numerous configurations
during subunit assembly give rise to a variety of receptors with different functional properties …

Hypothalamic feeding circuits have been identified as having innate synaptic plasticity,
mediating adaption to the changing metabolic milieu by controlling responses to feeding …