Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Endometrial cancer is the most common gynaecological cancer in high income countries
and its incidence is rising globally. Although an ageing population and fewer benign …

Objectives The tumor microenvironment (TME) play important roles in progression of
endometrial carcinoma (EC). We aimed to assess the cell populations in TME of EC …

Endometrial cancer represents the fifth most common cancer in women, and the most
common gynecological malignancy in developed countries [1]. Although endometrial cancer …

The human endometrium is a unique tissue undergoing important changes through the
menstrual cycle. Under the exposure of different risk factors in a woman's lifetime, normal …

Endometrial carcinosarcoma is a rare and aggressive high-grade endometrial carcinoma
with secondary sarcomatous trans-differentiation (conversion theory). The clinical …

Over the past decade, our understanding of endometrial cancer has changed dramatically
from the two-tiered clinicopathologic classification system of type I and type II endometrial …

We assessed the landscape of diagnostic pathology practice and how molecular
classification could potentially impact management of patients with endometrial cancer by …

Abstract Lysyl oxidase-like 2 (LOXL2) is a member of the scavenger receptor cysteine-rich
(SRCR) repeat carrying LOX family. Although LOXL2 is suspected to be involved in histone …

Early detection of endometrial cancer, especially its precancers, remains a critical and
evolving issue in patient management and the quest to decrease mortality due to …