The regulation of angiogenesis by hypoxia is an important component of homeostatic
mechanisms that link vascular oxygen supply to metabolic demand. Molecular …

Adenosine is a key endogenous molecule that regulates tissue function by activating four G-
protein-coupled adenosine receptors: A1, A2A, A2B and A3. Cells of the immune system …

Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Aerobic exercise training leads to cardiovascular changes that markedly increase aerobic
power and lead to improved endurance performance. The functionally most important …

Atherosclerosis is a highly prevalent disease that can significantly increase the risk of major
vascular events, such as myocardial or cerebral infarctions. The anoxemia theory states that …

Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …

We evaluated the effects of nitric oxide (NO) generators and endogenous production of NO
elicited by substance P (SP) in the angiogenesis process. Angiogenesis was monitored in …

Low oxygen tension influences tumor progression by enhancing angiogenesis; and histone
deacetylases (HDAC) are implicated in alteration of chromatin assembly and tumorigenesis …

Angiogenesis is the growth of blood vessels from the existing vasculature. The field of
angiogenesis has grown enormously in the past 30 years, with only 40 papers published in …

BACKGROUND Hypoxia inducible factor‐1 (HIF‐1) plays a critical role in angiogenesis
during vascular development. The authors tested the hypothesis that HIF‐1 expression …