Structural and dynamic studies of chromatin by solid-state NMR spectroscopy
CP Jaroniec - Current Opinion in Structural Biology, 2024 - Elsevier
Chromatin is a complex of DNA with histone proteins organized into nucleosomes that
regulates genome accessibility and controls transcription, replication and repair by …
regulates genome accessibility and controls transcription, replication and repair by …
MAD—microbial (origin of) Alzheimer's disease hypothesis: from infection and the antimicrobial response to disruption of key copper-based systems
JH Min, H Sarlus, RA Harris - Frontiers in Neuroscience, 2024 - frontiersin.org
Microbes have been suspected to cause Alzheimer's disease since at least 1908, but this
has generally remained unpopular in comparison to the amyloid hypothesis and the …
has generally remained unpopular in comparison to the amyloid hypothesis and the …
[HTML][HTML] Pathological Involvement of Protein Phase Separation and Aggregation in Neurodegenerative Diseases
Y Wu, B Ma, C Liu, D Li, G Sui - International Journal of Molecular …, 2024 - mdpi.com
Neurodegenerative diseases are the leading cause of human disability and immensely
reduce patients' life span and quality. The diseases are characterized by the functional loss …
reduce patients' life span and quality. The diseases are characterized by the functional loss …
[HTML][HTML] Proteins Associated with Neurodegenerative Diseases: Link to DNA Repair
SN Khodyreva, NS Dyrkheeva, OI Lavrik - Biomedicines, 2024 - mdpi.com
The nervous system is susceptible to DNA damage and DNA repair defects, and if DNA
damage is not repaired, neuronal cells can die, causing neurodegenerative diseases in …
damage is not repaired, neuronal cells can die, causing neurodegenerative diseases in …
Unravelling the Interplay between Biomolecular Condensates and RNA in Cancer and Diseases
P Poltronieri, S Joardar - Journal of Biological Regulators and …, 2024 - digital.csic.es
Biomolecular condensates (BCs), including membraneless organelles, are basically
Ribonucleic acid (RNA)-protein complexes that are emerging as a potential candidate …
Ribonucleic acid (RNA)-protein complexes that are emerging as a potential candidate …
Tau condensation on DNA and localization on centromeres: A potential link to cell division
Tau protein, traditionally recognized for stabilizing microtubules and forming pathological
aggregates, has recently been observed to form condensates in various contexts. While its …
aggregates, has recently been observed to form condensates in various contexts. While its …
Coffee and Alzheimer's disease
F Mirzaei, L Agbaria, K Bhatnagar… - Progress in brain …, 2024 - pubmed.ncbi.nlm.nih.gov
Coffee, a universally consumed beverage, is known to contain thousands of bioactive
constituents that have garnered interest due to their potential neuroprotective effects against …
constituents that have garnered interest due to their potential neuroprotective effects against …