The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

Hydrogenation is one of the most fundamental transformations in organic synthesis, and its
industrial applications span from fine chemicals to pharmaceuticals synthesis. 1− 3 Direct …

A catalytic protocol for the enantio-and diastereoselective reduction of α-substituted-β-keto
carbonitriles is described. The reaction involves a DKR-ATH process with the simultaneous …

An iodine-catalyzed Ritter-type amination of nonactivated C–H bonds is presented enabling
the formation of 1, 3-α-tertiary diamines. A sulfamidyl radical serves as the promoter in a …

We highlight recent developments of catalytic transfer hydrogenation of ketones promoted
by transition metals, while placing it within its historical context. Since optically active …

A highly enantioselective method for the complete hydrogenation of pyrimidinium salts using
Ir/(S, S)-f-Binaphane complex as the catalyst was presented in this study. This approach …

The methods to distinguish between amines are rarely investigated. In this article, a bond
energy enabled amine distinguishing strategy is reported. With (trifluoromethyl) alkenes as …

A new strategy for direct access to unreported α-cyanato-α′-carbonyl sulfoxonium ylides is
reported. The developed open-flask operation is a catalyst-, metal-and additive-free green …

Terpenes represent a promising renewable feedstock for the substitution of fossil resources
in the synthesis of renewable platform chemicals, like diamines. This work describes the …

Oxycyanation of alkenes would allow the direct construction of useful β‐hydroxy nitrile
scaffolds. However, only limited examples of such reactions have been reported, and some …