G protein-coupled receptors (GPCRs) play a key role in regulating the homeostasis of the
internal environment and are closely associated with tumour progression as major …

As negative modulators of G-protein-coupled receptors (GPCRs) signaling, regulators of G
protein signaling (RGS) proteins facilitate various downstream cellular signalings through …

Osteosarcoma (OS), the most common primary malignancy of the bone, has a poor
prognosis due to its high mortality rate and high potential for metastasis. Thus, it is urgently …

Background A major challenge in stage II colorectal carcinoma is to identify patients with
increased risk of recurrence. Biomarkers that distinguish patients with poor prognosis from …

Osteosarcoma is a highly mortal bone tumor, with a high metastatic potential, promoted in
part by the enzyme procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2). Increasing …

Osteosarcoma is the most common primary malignancy of bone in children and adolescents.
Others and our previous studies have shown that Yes-associated protein …

Long non-coding RNA (lncRNA) HOXA cluster antisense RNA 3 (HOXA-AS3) regulates the
progression of several types of human malignancy. However, the role and potential …

Objective Bone is a highly dynamic organ that undergoes constant bone formation and
remodeling, and glucose as a major nutrient is necessary for bone formation and …

Background Acute respiratory distress syndrome (ARDS) is a disease with high mortality
and morbidity. Regulator of G protein signaling protein 6 (RGS6), identified as a tumor …

Chondrosarcoma (CHS) is a rare type of soft sarcoma with increased production of cartilage
matrix arising from soft bone tissues. Currently, surgical resection is the primary clinical …