Platinum‐induced peripheral neurotoxicity: from pathogenesis to treatment

NP Staff, G Cavaletti, B Islam… - Journal of the …, 2019 - Wiley Online Library
Platinum‐induced peripheral neurotoxicity (PIPN) is a common side effect of platinum‐
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …

Platinum compounds in children with cancer: toxicity and clinical management

A Ruggiero, G Trombatore, S Triarico, R Arena… - Anti-cancer …, 2013 - journals.lww.com
Platinum compounds are widely used in the treatment of pediatric tumors such as
neuroblastoma, germ-cell tumors, osteosarcoma, retinoblastoma, hepatoblastoma, brain …

Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development

KRG Knight, DF Kraemer, EA Neuwelt - Journal of Clinical Oncology, 2005 - ascopubs.org
Purpose To describe the frequency and severity of ototoxicity in a series of pediatric patients
treated with platinum-based chemotherapy. Patients and Methods Serial audiologic …

Predicting cisplatin ototoxicity in children: the influence of age and the cumulative dose

Y Li, RB Womer, JH Silber - European Journal of Cancer, 2004 - Elsevier
The aim of this study was to determine the risk factors for high-frequency hearing loss in
children treated with cisplatin. We scored off-treatment pure-tone audiograms from 153 …

Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer

C Bokemeyer, CC Berger, JT Hartmann… - British journal of …, 1998 - nature.com
This study evaluates the degree and relevance of persisting ototoxicity after cisplatin-based
standard-dose chemotherapy for testicular cancer, with emphasis on identification of …

Platinum compound-related ototoxicity in children: long-term follow-up reveals continuous worsening of hearing loss

P Bertolini, M Lassalle, G Mercier… - Journal of pediatric …, 2004 - journals.lww.com
Objectives: The purpose of this study was to evaluate the severity of hearing loss after
cisplatin and/or carboplatin treatment in young children and to analyze its evolution and its …

Cisplatin ototoxicity in children: a practical grading system

PR Brock, SC Bellman, EC Yeomans… - Medical and …, 1991 - Wiley Online Library
A long‐term follow‐up study was carried out to assess ototoxicity in children who had been
treated for a malignant tumour with “standard dose” cisplatin (60–; 100 mg/m2 per course) …

Ototoxicity from cisplatin therapy in childhood cancer

PP Coradini, L Cigana, SGA Selistre… - Journal of pediatric …, 2007 - journals.lww.com
Cisplatin has been associated with hearing damage. It is usually irreversible, bilateral, and
characterized by high-frequency sensorineural hearing loss. This study was carried out to …

Ototoxicity after radiotherapy for head and neck tumors

N Bhandare, PJ Antonelli, CG Morris… - International Journal of …, 2007 - Elsevier
Purpose: To investigate the incidence of radiation-induced ototoxicity according to the total
dose delivered to specific parts of the auditory system, fractionation, and chemotherapy …

Sensorineural hearing loss in patients treated for nasopharyngeal carcinoma: a prospective study of the effect of radiation and cisplatin treatment.

DL Kwong, WI Wei, JS Sham, WK Ho… - … journal of radiation …, 1996 - europepmc.org
PURPOSE: The pattern of sensorineural hearing loss (SNHL) after primary treatment for
nasopharyngeal carcinoma (NPC) was studied, and the effect of cisplatin, radiotherapy …