Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients
carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9 …

One hundred and fifty years since Nikolaus Friedreich's first description of the degenerative
ataxic syndrome which bears his name, his description remains at the core of the classical …

Friedreich's ataxia (FRDA), a neurodegenerative disease characterized by ataxia and other
neurological features, affects 1 in 50,000–100,000 individuals in the USA. However, FRDA …

Friedreich ataxia (FRDA) is a multisystem disorder affecting 1 in 50,000–100,000 person in
the United States. Traditionally viewed as a neurodegenerative disease, FRDA patients also …

Friedreich Ataxia (FRDA) is an autosomal recessive disease in which a mitochondrial
protein, frataxin, is severely decreased in its expression. In addition to progressive ataxia …

Objectives/Aims This is an open‐label trial of the safety of interferon gamma‐1b (IFN‐γ) and
its effect on frataxin levels and neurologic measures in 12 children with Friedreich ataxia …

Background Friedreich's ataxia (FA) is a rare multisystemic disorder which can cause
premature death. Objectives To investigate predictors of survival in FA. Methods Within a …

Friedreich's ataxia (FA) is a life-threatening autosomal recessive disorder characterized by
neurological and cardiac dysfunction. Arrhythmias and heart failure are the main cause of …

Friedreich's ataxia is the commonest autosomal recessive ataxia among population of
European descent. Despite the huge advances performed in the last decades, a cure still …

Genetic disorders that disrupt the structure and function of the cardiovascular system and the
peripheral nervous system are common enough to be encountered in routine cardiovascular …