[HTML][HTML] Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers

L Zhang, B Ye, Z Chen, ZS Chen - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Chemotherapy is one of the important methods to treat cancer, and the emergence of
multidrug resistance (MDR) is one major cause for the failure of cancer chemotherapy …

Drug resistance in ovarian cancer: from mechanism to clinical trial

L Wang, X Wang, X Zhu, L Zhong, Q Jiang, Y Wang… - Molecular Cancer, 2024 - Springer
Ovarian cancer is the leading cause of gynecological cancer-related death. Drug resistance
is the bottleneck in ovarian cancer treatment. The increasing use of novel drugs in clinical …

Epicardial HDAC3 promotes myocardial growth through a novel microRNA pathway

J Jang, G Song, SM Pettit, Q Li, X Song, C Cai… - Circulation …, 2022 - Am Heart Assoc
Background: Establishment of the myocardial wall requires proper growth cues from
nonmyocardial tissues. During heart development, the epicardium and epicardium-derived …

Nanobubbles containing PD-L1 Ab and miR-424 mediated PD-L1 blockade, and its expression inhibition to enable and potentiate hepatocellular carcinoma …

Y Liu, Q Xie, Y Ma, C Lin, J Li, B Hu, C Liu… - International Journal of …, 2022 - Elsevier
Immune checkpoint inhibitors (ICI) therapy is the main type of immunotherapy for cancer.
Current clinical trials are focused on enhancing anti-tumor effects through combinations of …

The Importance of the Immune System and Molecular Cell Signaling Pathways in the Pathogenesis and Progression of Lung Cancer

J Smok-Kalwat, P Mertowska, S Mertowski… - International Journal of …, 2023 - mdpi.com
Lung cancer is a disease that in recent years has become one of the greatest threats to
modern society. Every year there are more and more new cases and the percentage of …

[HTML][HTML] Exosomal miRNA-223-3p as potential biomarkers in patients with cerebral small vessel disease cognitive impairment

W Zhao, W Sun, S Li, Y Jiao, Z Wang, T Wu… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Cerebrovascular disease is a common clinical illness. Many patients with
cerebrovascular disease can be accompanied by cognitive impairment. The exosomal …

Determination of T-cell clonality and expression profiles of Toll-like receptors signaling pathway genes and related miRNAs in patients with mycosis fungoides

M Seçme, Y Dodurga, NÇ Demirkan, N Kaçar… - Gene, 2024 - Elsevier
Cutaneous T-cell lymphomas (CTCL) encompass a group of diseases characterized by the
presence of malignant clonal CD4+ T lymphocytes in the skin. Mycosis fungoides (MF) is the …

Long non-coding RNA THRIL is upregulated in coronary heart disease and binds to microRNA-424 to upregulate TXNIP in mice

L Lin, J Bao - Microvascular Research, 2021 - Elsevier
Cardiovascular disease, particularly coronary heart disease (CHD), is one of the diseases
with the highest fatality. The close correlation between long non-coding RNAs (lncRNAs) …

[HTML][HTML] Non-coding RNAs: are they the protagonist or antagonist in the regulation of leukemia?

M Bhattacharya, RK Gutti - American Journal of Translational …, 2022 - ncbi.nlm.nih.gov
The idea of functional non-coding RNAs is taking precedence over the previous notion
which believed that they only comprise the auxiliary and junk material of the genome. Newer …

MicroRNAs as Prognostic Biomarkers and Therapeutic Targets in Chondrosarcoma

P Skipar, M Dey, J Piątkowski, D Sulejczak… - International Journal of …, 2024 - mdpi.com
Chondrosarcoma, the second most common primary malignant bone tumor, originates from
cartilaginous tissue and accounts for almost 20% of all primary bone tumors. The …